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WILLIAM SOMERS, M.D.
M.D.
Orthopaedic Surgery Physician
NPI: 1891858486Individual
Specialties, Licenses & Credentials
Orthopaedic Surgery PhysicianPrimary
Orthopaedic Surgery
Code: 207X00000X
18059(NC)
Research & Publications (20)
A RhoGEF and Rho family GTPase-activating protein complex links the contractile ring to cortical microtubules at the onset of cytokinesis.
PMID 12530961·Dev Cell·2003
7-preclinical
Swift residue-screening identifies key N-glycosylated asparagines sufficient for surface expression of neuroglycoprotein Lingo-1.
PMID 19254717·FEBS Lett·2009
8-other
Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.
PMID 19241384·Protein Sci·2009
7-preclinical
Protein phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions.
PMID 19204120·Genes Dev·2009
7-preclinical
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
PMID 18042673·Protein Sci·2008
8-other
Expression, purification and crystallization of the ecto-enzymatic domain of rat E-NTPDase1 CD39.
PMID 18997343·Acta Crystallogr Sect F Struct Biol Cryst Commun·2008
7-preclinical
Drosophila neuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis.
PMID 18209103·J Cell Biol·2008
6-review
Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.
PMID 17805297·Nature·2007
7-preclinical
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
PMID 17005555·J Biol Chem·2006
7-preclinical
A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions.
PMID 16749923·BMC Genet·2006
7-preclinical
A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis.
PMID 16574278·Peptides·2006
7-preclinical
Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors.
PMID 16335920·J Med Chem·2005
4-observational
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.
PMID 15974587·J Med Chem·2005
7-preclinical
Catalytic domain crystal structure of protein kinase C-theta (PKCtheta).
PMID 15364937·J Biol Chem·2004
8-other
Understanding the selectivity of genistein for human estrogen receptor-beta using X-ray crystallography and computational methods.
PMID 15576033·Structure·2004
8-other
Structure-based design of estrogen receptor-beta selective ligands.
PMID 15548008·J Am Chem Soc·2004
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3634 SPARROW HAWK CRST
HILLSBOROUGH, NC 27278 - Phone
- (919) 245-3000
Quick Facts
- NPI
- 1891858486
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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