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JOSEPH GRODEN, MD
MD
Ophthalmology Physician
NPI: 1912905571Individual
Specialties, Licenses & Credentials
Ophthalmology PhysicianPrimary
Ophthalmology
Code: 207W00000X
42474(MA)
Research & Publications (20)
Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates.
PMID 19329795·J Biol Chem·2009
8-other
The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl terminus.
PMID 18474248·Gastroenterology·2008
7-preclinical
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.
PMID 17615082·Genome Biol·2007
4-observational
Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis.
PMID 17297457·Oncogene·2007
8-other
A placebo double-blind pilot study of dextromethorphan for problematic behaviors in children with autism.
PMID 17175572·Autism·2007
2-rct
The Werner and Bloom syndrome proteins catalyze regression of a model replication fork.
PMID 17115688·Biochemistry·2006
8-other
beta-Catenin/Wnt signaling regulates expression of the membrane type 3 matrix metalloproteinase in gastric cancer.
PMID 16651426·Cancer Res·2006
7-preclinical
The treatment of the behavioral sequelae of autism with dextromethorphan: a case report.
PMID 16134036·J Autism Dev Disord·2005
5-case
BLM helicase complements disrupted type II telomere lengthening in telomerase-negative sgs1 yeast.
PMID 15994923·Cancer Res·2005
8-other
RecQ family members combine strand pairing and unwinding activities to catalyze strand exchange.
PMID 15845538·J Biol Chem·2005
7-preclinical
The APC tumor suppressor promotes transcription-independent apoptosis in vitro.
PMID 15755874·Mol Cancer Res·2005
7-preclinical
BLM helicase is activated in BCR/ABL leukemia cells to modulate responses to cisplatin.
PMID 15750625·Oncogene·2005
7-preclinical
Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors.
PMID 15665292·Cancer Res·2005
7-preclinical
Crosslinks and crosstalk: human cancer syndromes and DNA repair defects.
PMID 15607958·Cancer Cell·2004
6-review
Isoforms of the APC tumor suppressor and their ability to inhibit cell growth and tumorigenicity.
PMID 15273719·Oncogene·2004
8-other
Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2.
PMID 15229185·Hum Mol Genet·2004
4-observational
Alternative splicing of the APC gene in the neural retina and retinal pigment epithelium.
PMID 15218453·Mol Vis·2004
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 13 E HOYLE ST
NORWOOD, MA 02062 - Phone
- (781) 769-0987
Quick Facts
- NPI
- 1912905571
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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