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JOHNATHAN SHANKLIN, MD
MD
Anesthesiology Physician
NPI: 1922685361IndividualAccepts Medicare
Specialties, Licenses & Credentials
Anesthesiology PhysicianPrimary
Anesthesiology
Code: 207L00000X
35.152615(OH)
CMS Specialties
PrimaryANESTHESIOLOGY
Education
OTHER
Class of 2021
Research & Publications (20)
Desaturases: emerging models for understanding functional diversification of diiron-containing enzymes.
PMID 19363032·J Biol Chem·2009
6-review
Revealing the catalytic potential of an acyl-ACP desaturase: tandem selective oxidation of saturated fatty acids.
PMID 18796606·Proc Natl Acad Sci U S A·2008
8-other
The Arabidopsis stearoyl-acyl carrier protein-desaturase family and the contribution of leaf isoforms to oleic acid synthesis.
PMID 17072561·Plant Mol Biol·2007
8-other
Modulating seed beta-ketoacyl-acyl carrier protein synthase II level converts the composition of a temperate seed oil to that of a palm-like tropical oil.
PMID 17360594·Proc Natl Acad Sci U S A·2007
8-other
Identification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approach.
PMID 17201914·BMC Plant Biol·2007
8-other
Stereochemistry of Delta4 dehydrogenation catalyzed by an ivy (Hedera helix) Delta9 desaturase homolog.
PMID 17406726·Org Biomol Chem·2007
8-other
The crystal structure of the ivy Delta4-16:0-ACP desaturase reveals structural details of the oxidized active site and potential determinants of regioselectivity.
PMID 17463003·J Biol Chem·2007
4-observational
A single mutation in the castor Delta9-18:0-desaturase changes reaction partitioning from desaturation to oxidase chemistry.
PMID 17088542·Proc Natl Acad Sci U S A·2006
8-other
In vitro enzymatic oxidation of a fluorine-tagged sulfido substrate analogue: a 19F NMR investigation.
PMID 16534835·Magn Reson Chem·2006
8-other
Linking enzyme sequence to function using Conserved Property Difference Locator to identify and annotate positions likely to control specific functionality.
PMID 16318626·BMC Bioinformatics·2005
7-preclinical
A multifunctional acyl-acyl carrier protein desaturase from Hedera helix L. (English ivy) can synthesize 16- and 18-carbon monoene and diene products.
PMID 15939740·J Biol Chem·2005
8-other
Effect of substrate on the diiron(III) site in stearoyl acyl carrier protein delta 9-desaturase as disclosed by cryoreduction electron paramagnetic resonance/electron nuclear double resonance spectroscopy.
PMID 15667224·Biochemistry·2005
8-other
A structural model of the plant acyl-acyl carrier protein thioesterase FatB comprises two helix/4-stranded sheet domains, the N-terminal domain containing residues that affect specificity and the C-terminal domain containing catalytic residues.
PMID 15531590·J Biol Chem·2005
8-other
Identification of the Arabidopsis palmitoyl-monogalactosyldiacylglycerol delta7-desaturase gene FAD5, and effects of plastidial retargeting of Arabidopsis desaturases on the fad5 mutant phenotype.
PMID 15579662·Plant Physiol·2004
8-other
Substrate binding and the presence of ferredoxin affect the redox properties of the soluble plant Delta9-18:0-acyl carrier protein desaturase.
PMID 15514788·Chem Commun (Camb)·2004
8-other
Switching desaturase enzyme specificity by alternate subcellular targeting.
PMID 15240892·Proc Natl Acad Sci U S A·2004
8-other
Evidence linking the Pseudomonas oleovorans alkane omega-hydroxylase, an integral membrane diiron enzyme, and the fatty acid desaturase family.
PMID 12804773·FEBS Lett·2003
8-other
Azide and acetate complexes plus two iron-depleted crystal structures of the di-iron enzyme delta9 stearoyl-acyl carrier protein desaturase. Implications for oxygen activation and catalytic intermediates.
PMID 12704186·J Biol Chem·2003
8-other
Exploring the hydroxylation-dehydrogenation connection: novel catalytic activity of castor stearoyl-ACP Delta(9) desaturase.
PMID 11916411·J Am Chem Soc·2002
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 11100 EUCLID AVE
CLEVELAND, OH 44106 - Phone
- (270) 305-2858
Quick Facts
- NPI
- 1922685361
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 5
- Publications
- 20
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