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WILLIAM ROESKE, MD
MD
Cardiovascular Disease Physician
NPI: 1932279494Individual
Specialties, Licenses & Credentials
Cardiovascular Disease PhysicianPrimary
Internal Medicine — Cardiovascular Disease
Code: 207RC0000X
9415(AZ)
Research & Publications (20)
Sustained morphine treatment augments capsaicin-evoked calcitonin gene-related peptide release from primary sensory neurons in a protein kinase A- and Raf-1-dependent manner.
PMID 19491327·J Pharmacol Exp Ther·2009
7-preclinical
Sustained cannabinoid agonist treatment augments CGRP release in a PKA-dependent manner.
PMID 19387418·Neuroreport·2009
7-preclinical
Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia.
PMID 18976650·Eur J Pharmacol·2008
7-preclinical
Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner.
PMID 18328477·Eur J Pharmacol·2008
7-preclinical
Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling.
PMID 18162180·Eur J Pharmacol·2008
7-preclinical
Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.
PMID 17322005·Mol Pharmacol·2007
7-preclinical
Mediating delta-opioid-initiated heart protection via the beta2-adrenergic receptor: role of the intrinsic cardiac adrenergic cell.
PMID 17369460·Am J Physiol Heart Circ Physiol·2007
7-preclinical
Chronic morphine-mediated adenylyl cyclase superactivation is attenuated by the Raf-1 inhibitor, GW5074.
PMID 16750187·Eur J Pharmacol·2006
7-preclinical
Morphine promotes phosphorylation of the human delta-opioid receptor at serine 363.
PMID 16135360·Eur J Pharmacol·2005
4-observational
Antinociception depends on the presence of G protein gamma2-subunits in brain.
PMID 15680258·Eur J Pharmacol·2005
4-observational
Neuroendocrine properties of intrinsic cardiac adrenergic cells in fetal rat heart.
PMID 15458949·Am J Physiol Heart Circ Physiol·2005
7-preclinical
Mutation S363A in the human delta-opioid receptor selectively reduces down-regulation by a peptide agonist.
PMID 14757159·Eur J Pharmacol·2004
4-observational
Postural position and neurocardiogenic syncope in late pregnancy.
PMID 14609615·Am J Cardiol·2003
5-case
Molecular mechanisms of excitatory signaling upon chronic opioid agonist treatment.
PMID 14607258·Life Sci·2003
6-review
Converging protein kinase pathways mediate adenylyl cyclase superactivation upon chronic delta-opioid agonist treatment.
PMID 12660310·J Pharmacol Exp Ther·2003
7-preclinical
(2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain.
PMID 12538822·J Pharmacol Exp Ther·2003
7-preclinical
Agonist-specific down-regulation of the human delta-opioid receptor.
PMID 12505529·Eur J Pharmacol·2003
7-preclinical
Involvement of Raf-1 in chronic delta-opioid receptor agonist-mediated adenylyl cyclase superactivation.
PMID 12223234·Eur J Pharmacol·2002
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1501 N CAMPBELL AVE
TUCSON, AZ 85724 - Phone
- (520) 694-8888
Quick Facts
- NPI
- 1932279494
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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