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DAVID KASSEL, MD
MD
Emergency Medicine Physician
NPI: 1942333141Individual
Specialties, Licenses & Credentials
Emergency Medicine PhysicianPrimary
Emergency Medicine
Code: 207P00000X
G043890(CA)
Research & Publications (18)
Applications of high-throughput ADME in drug discovery.
PMID 15183334·Curr Opin Chem Biol·2004
6-review
Combinatonial chemistry and mass spectrometry in the 21st century drug discovery laboratory.
PMID 11712247·Chem Rev·2001
6-review
Pharmacokinetic, pharmacodynamic, and efficacy profiles of alogliptin, a novel inhibitor of dipeptidyl peptidase-4, in rats, dogs, and monkeys.
PMID 18538760·Eur J Pharmacol·2008
7-preclinical
Structure-based design and synthesis of benzimidazole derivatives as dipeptidyl peptidase IV inhibitors.
PMID 18346892·Bioorg Med Chem Lett·2008
7-preclinical
Parallel supercritical fluid chromatography/mass spectrometry system for high-throughput enantioselective optimization and separation.
PMID 17900596·J Chromatogr A·2007
8-other
Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV.
PMID 17441705·J Med Chem·2007
7-preclinical
Phosphopeptides enrichment using on-line two-dimensional strong cation exchange followed by reversed-phase liquid chromatography/mass spectrometry.
PMID 16750159·Anal Biochem·2006
7-preclinical
Cell-based assay for screening 11beta-hydroxysteroid dehydrogenase inhibitors using liquid chromatography/tandem mass spectrometry detection.
PMID 16636996·Rapid Commun Mass Spectrom·2006
7-preclinical
Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.
PMID 16101009·Comb Chem High Throughput Screen·2005
8-other
Automated high throughput ADME assays for metabolic stability and cytochrome P450 inhibition profiling of combinatorial libraries.
PMID 15019033·J Pharm Biomed Anal·2004
8-other
Fragmentation of tunichrome Sp-1 is dominated by an unusual gas-phase intramolecular rearrangement.
PMID 14595860·J Mass Spectrom·2003
7-preclinical
Structure of a c-kit product complex reveals the basis for kinase transactivation.
PMID 12824176·J Biol Chem·2003
8-other
Improvement of "hit-to-lead" optimization by integration of in vitro HTS experimental models for early determination of pharmacokinetic properties.
PMID 12470275·Comb Chem High Throughput Screen·2002
6-review
High-throughput mass-directed parallel purification incorporating a multiplexed single quadrupole mass spectrometer.
PMID 12141664·Anal Chem·2002
8-other
Application of parallel liquid chromatography/mass spectrometry for high throughput microsomal stability screening of compound libraries.
PMID 11841071·J Am Soc Mass Spectrom·2002
8-other
Mass-directed fractionation and isolation of pharmaceutical compounds by packed-column supercritical fluid chromatography/mass spectrometry.
PMID 11746870·Rapid Commun Mass Spectrom·2001
8-other
Differences in phosphorylation of human and chicken stathmin by MAP kinase.
PMID 11135364·J Cell Biochem·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 3035 N. MAIN STREET
SOQUEL, CA 95073 - Phone
- (831) 688-8680
Quick Facts
- NPI
- 1942333141
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 18
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