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WILLIAM FARRIS, MD
MD
Pediatrics Physician
NPI: 1962421743Individual
Specialties, Licenses & Credentials
Pediatrics PhysicianPrimary
Pediatrics
Code: 208000000X
036055059(IL)
Research & Publications (11)
Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy.
PMID 17591969·Am J Pathol·2007
7-preclinical
Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease.
PMID 17321748·Neurobiol Dis·2007
7-preclinical
Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families.
PMID 17244626·J Biol Chem·2007
8-other
Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.
PMID 15850385·Biochemistry·2005
7-preclinical
Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.
PMID 15751228·J Neuropathol Exp Neurol·2005
7-preclinical
Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria.
PMID 15285718·Biochem J·2004
7-preclinical
Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein.
PMID 15039230·Am J Pathol·2004
4-observational
Live discussion: Amyloid-beta degradation: the forgotten half of Alzheimer's disease. 12 September 2002.
PMID 14765518·J Alzheimers Dis·2003
8-other
Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.
PMID 14687544·Neuron·2003
4-observational
Kinetics of amyloid beta-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays.
PMID 12867419·J Biol Chem·2003
8-other
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
PMID 12634421·Proc Natl Acad Sci U S A·2003
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 611 W PARK ST
URBANA, IL 61801 - Phone
- (217) 383-3311
Quick Facts
- NPI
- 1962421743
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 11
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