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JONATHAN CHERNOFF, MD
MD
Medical Oncology Physician
NPI: 1962741694Individual
Specialties, Licenses & Credentials
Medical Oncology PhysicianPrimary
Internal Medicine — Medical Oncology
Code: 207RX0202X
MD034646E(PA)
Research & Publications (20)
PAK kinase regulates Rac GTPase and is a potential target in human schwannomas.
PMID 19409384·Exp Neurol·2009
8-other
Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases.
PMID 19435845·Proc Natl Acad Sci U S A·2009
7-preclinical
p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.
PMID 19124833·Blood·2009
7-preclinical
Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development.
PMID 19557173·PLoS One·2009
7-preclinical
Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells.
PMID 19435911·Cancer Res·2009
8-other
PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics.
PMID 18940914·J Cell Sci·2008
7-preclinical
Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.
PMID 18768391·Blood·2008
7-preclinical
Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes.
PMID 18054038·J Mol Cell Cardiol·2008
7-preclinical
An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase.
PMID 18420139·Chem Biol·2008
7-preclinical
Regulation of protein tyrosine phosphatase 1B by sumoylation.
PMID 17159996·Nat Cell Biol·2007
7-preclinical
Specificity profiling of Pak kinases allows identification of novel phosphorylation sites.
PMID 17392278·J Biol Chem·2007
4-observational
The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.
PMID 17001318·Oncogene·2007
7-preclinical
alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini.
PMID 17911169·J Cell Sci·2007
8-other
A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.
PMID 16837009·J Mol Biol·2006
8-other
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
PMID 16492808·J Cell Biol·2006
7-preclinical
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties.
PMID 16581795·Mol Cell Biol·2006
4-observational
Regulation of the catalytic activity of PTP1B: roles for cell adhesion, tyrosine residue 66, and proline residues 309 and 310.
PMID 16289152·Exp Cell Res·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 333 COTTMAN AVE, W455
PHILADELPHIA, PA 19111 - Phone
- (215) 728-5319
Quick Facts
- NPI
- 1962741694
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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