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JOYCE GOTTESFELD, MD
MD
Obstetrics & Gynecology Physician
NPI: 1992832943Individual
Specialties, Licenses & Credentials
Obstetrics & Gynecology PhysicianPrimary
Obstetrics & Gynecology
Code: 207V00000X
33615(CO)
Research & Publications (20)
Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors.
PMID 19362838·Bioorg Med Chem Lett·2009
8-other
Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate.
PMID 18974832·PLoS One·2008
7-preclinical
Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases.
PMID 18953021·J Biol Chem·2008
7-preclinical
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.
PMID 18829438·Proc Natl Acad Sci U S A·2008
7-preclinical
Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia.
PMID 18820300·Nucleic Acids Res·2008
8-other
Targeting specific gene by alkylating pyrrole-imidazole polyamides.
PMID 18776404·Nucleic Acids Symp Ser (Oxf)·2008
8-other
HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model.
PMID 18463734·PLoS One·2008
7-preclinical
Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.
PMID 18413791·Mol Cancer Ther·2008
7-preclinical
Small molecules affecting transcription in Friedreich ataxia.
PMID 17826840·Pharmacol Ther·2007
6-review
Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates.
PMID 17170006·Nucleic Acids Res·2007
4-observational
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia.
PMID 16921367·Nat Chem Biol·2006
8-other
A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate.
PMID 16861886·Cell Cycle·2006
8-other
DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia.
PMID 16857735·Proc Natl Acad Sci U S A·2006
8-other
Alkylation of duplex DNA in nucleosome core particles by duocarmycin SA and yatakemycin.
PMID 16415862·Nat Chem Biol·2006
8-other
Induced fit and "lock and key" recognition of 5S RNA by zinc fingers of transcription factor IIIA.
PMID 16405997·J Mol Biol·2006
7-preclinical
Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides.
PMID 15766247·Biochemistry·2005
8-other
Role of DNA sequence in the binding specificity of synthetic basic-helix-loop-helix domains.
PMID 15593070·Chembiochem·2005
8-other
Nucleosomes in solution exist as a mixture of twist-defect states.
PMID 15567414·J Mol Biol·2005
7-preclinical
Arresting cancer proliferation by small-molecule gene regulation.
PMID 15556009·Chem Biol·2004
8-other
Regulation of gene expression with pyrrole-imidazole polyamides.
PMID 15288953·J Biotechnol·2004
6-review
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 10400 E ALAMEDA AVE
DENVER, CO 80247 - Phone
- (303) 338-4545
Quick Facts
- NPI
- 1992832943
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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