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REUBEN SIRAGANIAN, M.D.
M.D.
Allergy Physician
NPI: 1992948525Individual
Specialties, Licenses & Credentials
Allergy PhysicianPrimary
Allergy & Immunology — Allergy
Code: 207KA0200X
107541-1(NY)
Research & Publications (20)
Mast cell signal transduction from the high-affinity IgE receptor.
PMID 14630197·Curr Opin Immunol·2003
6-review
FcepsilonRI-induced activation by low antigen concentrations results in nuclear signals in the absence of degranulation.
PMID 19540596·Mol Immunol·2009
7-preclinical
IgE-induced mast cell survival requires the prolonged generation of reactive oxygen species.
PMID 18768839·J Immunol·2008
7-preclinical
The low affinity IgG receptor Fc gamma RIIB contributes to the binding of the mast cell specific antibody, mAb BGD6.
PMID 18295888·Mol Immunol·2008
7-preclinical
TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells.
PMID 17977829·J Biol Chem·2007
7-preclinical
Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor alpha-subunit expression in the mammalian pinealocyte: a neuroendocrine/immune response link?
PMID 17728245·J Biol Chem·2007
7-preclinical
Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway.
PMID 17202354·J Immunol·2007
7-preclinical
Mast cell-specific gangliosides and FcepsilonRI follow the same endocytic pathway from lipid rafts in RBL-2H3 cells.
PMID 17164410·J Histochem Cytochem·2007
7-preclinical
Dendritic cell modulation by mast cells controls the Th1/Th2 balance in responding T cells.
PMID 16951316·J Immunol·2006
7-preclinical
Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.
PMID 16400030·Am J Pathol·2006
7-preclinical
Identification and characterization of undifferentiated mast cells in mouse bone marrow.
PMID 15718418·Blood·2005
7-preclinical
Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation.
PMID 15339843·Blood·2004
7-preclinical
Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.
PMID 15265912·J Immunol·2004
4-observational
Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.
PMID 14656219·Biochem J·2004
7-preclinical
Alterations in granule matrix and cell surface of focal adhesion kinase-deficient mast cells.
PMID 14634134·J Immunol·2003
7-preclinical
Phosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cells.
PMID 12417718·Mol Cell Biol·2002
7-preclinical
Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.
PMID 12145291·J Biol Chem·2002
7-preclinical
The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.
PMID 11971018·J Immunol·2002
7-preclinical
Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival.
PMID 11420049·Immunity·2001
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- NATIONAL INSTITUTES OF HEALTH, BUILDING 49, 1A16
BETHESDA, MD 20892 - Phone
- (301) 496-5105
Quick Facts
- NPI
- 1992948525
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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