Actin.smooth muscle Ab
Detects antibodies against smooth muscle actin, a muscle protein.
Why This Biomarker Matters
SMA antibodies are a hallmark of autoimmune hepatitis. Positive results indicate immune-mediated liver disease requiring prompt treatment with immunosuppressive therapy to prevent liver failure.
Overview
Smooth muscle actin antibodies (SMA) are autoantibodies your immune system produces against smooth muscle tissue in your body. These antibodies are strongly associated with autoimmune hepatitis, a serious liver inflammation condition. Elevated SMA indicates your immune system is attacking liver cells. This test is typically ordered when liver enzyme abnormalities are detected. Positive results typically require treatment with immunosuppressive medications to prevent liver damage and cirrhosis.
Technical Information (LOINC Codes)
Standardized laboratory codes for this biomarker
63210-9Primary63211-789520-1Available Lab Tests
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