Tissue transglutaminase Ab.IgA & IgG panel
Detects antibodies against tissue transglutaminase, a marker for celiac disease.
Why This Biomarker Matters
Elevated antibodies indicate celiac disease, requiring strict gluten avoidance to prevent intestinal damage, malabsorption, and long-term complications like anemia and osteoporosis.
Overview
This test measures antibodies (IgA and IgG) against tissue transglutaminase (tTG), a protein involved in celiac disease. When people with celiac disease consume gluten, their immune system attacks this protein, producing these antibodies. Elevated levels are highly suggestive of celiac disease or dermatitis herpetiformis. This is the primary screening test for celiac disease and helps confirm diagnosis in those with symptoms like digestive issues, fatigue, or nutrient deficiencies.
Technical Information (LOINC Codes)
Standardized laboratory codes for this biomarker
55727-2PrimaryAvailable Lab Tests
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