Clinical Trials
7
Total Trials
4
Recruiting
0
With Results
Recent Trials
Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes
NCT00001405Recruiting850 enrolled
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
NCT07284641Phase 2Recruiting25 enrolled
Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease
NCT06325709Phase 1/PHASE2Recruiting10 enrolled
Immune Disorder HSCT Protocol
NCT01821781Phase 2Active Not Recruiting20 enrolled
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer
NCT02108028Completed272 enrolled
Research Evidence
Peer-reviewed studies linked via MeSH term "Granulomatous Disease, Chronic" from the MEDLINE/PubMed database.
Sort:
Efficacy and Safety of Interferon-Gamma in Chronic Granulomatous Disease: a Systematic Review and Meta-analysis.
[object Object], [object Object], [object Object] et al. · J Clin Immunol · 2023
PMID: 36385358Meta-Analysis
"Oral Manifestations of Patients with Inherited Defect in Phagocyte Number or Function" a systematic review.
[object Object], [object Object], [object Object] et al. · Clin Immunol · 2021
PMID: 34271191Meta-Analysis
COVID-19 mimics on chest CT: a pictorial review and radiologic guide.
[object Object], [object Object], [object Object] et al. · Br J Radiol · 2021
Nocardiosis Associated with Primary Immunodeficiencies (Nocar-DIP): an International Retrospective Study and Literature Review.
[object Object], [object Object], [object Object] et al. · J Clin Immunol · 2020
PMID: 32920680Meta-Analysis
Chronic granulomatous disease as an SOS call for multicenter cooperative effort to prevent infections: A meta-analysis of the treatments.
[object Object], [object Object], [object Object] et al. · Ann Allergy Asthma Immunol · 2016
PMID: 27613462Meta-Analysis
The BTNL2 G16071A gene polymorphism increases granulomatous disease susceptibility: A meta-analysis including FPRP test of 8710 participants.
[object Object], [object Object], [object Object] et al. · Medicine (Baltimore) · 2016
Invasive fungal infections in patients with chronic granulomatous disease.
[object Object], [object Object], [object Object] et al. · Adv Exp Med Biol · 2013
PMID: 23654055Meta-Analysis
Non-Aspergillus fungal infections in chronic granulomatous disease.
[object Object], [object Object], [object Object] · Mycoses · 2013
PMID: 23369076Meta-Analysis
Osteomyelitis due to Aspergillus species in chronic granulomatous disease: an update of the literature.
[object Object], [object Object] · Mycoses · 2011
PMID: 21615532Meta-Analysis
Increased production of nitric oxide by neutrophils from patients with chronic granulomatous disease on interferon-gamma treatment.
[object Object], [object Object], [object Object] et al. · Int Immunopharmacol · 2012
PMID: 22330085RCT
Search all PubMed articles for Chronic granulomatous disease
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal connection between trachea and esophagus
Very frequent (80-99%)HP:0002575
Abnormality of neutrophils
Very frequent (80-99%)HP:0001874
COPD
Very frequent (80-99%)HP:0006510
Cutaneous photosensitivity
Very frequent (80-99%)HP:0000992
Enlarged liver
Very frequent (80-99%)HP:0002240
Flat, discolored area of skin
Very frequent (80-99%)HP:0012733
Hyperpigmented macules
Very frequent (80-99%)HP:0001034
Infantile hypertrophic pyloric stenosis
Very frequent (80-99%)HP:0002021
Intestinal malabsorption
Very frequent (80-99%)HP:0002024
Otitis media
Very frequent (80-99%)HP:0000388
Pyrexia
Very frequent (80-99%)HP:0001945
respiratory infections, recurrent
Very frequent (80-99%)HP:0002205
Sinusitis
Very frequent (80-99%)HP:0000246
Swollen lymph nodes in centre of chest
Very frequent (80-99%)HP:0100721
Eczema
Occasional (5-29%)HP:0000964
Infection in blood stream
Occasional (5-29%)HP:0100806
Inflammatory abnormality of the eye
Occasional (5-29%)HP:0100533
Large spleen
Occasional (5-29%)HP:0001744
Liver abscess
Occasional (5-29%)HP:0100523
Meningitis
Occasional (5-29%)HP:0001287
Open skin sore
Occasional (5-29%)HP:0200042
Red and swollen gums
Occasional (5-29%)HP:0000230
Related Conditions
Chronic granulomatous disease, type IV(child)
Chronic granulomatous disease, type IIA(child)
Chronic granulomatous disease, type I(child)
Chronic granulomatous disease, type IA(child)
Chronic granulomatous disease, type IVA(child)
Chronic granulomatous disease, type II(child)
Chronic granulomatous disease, type III(child)
Disorder of neutrophils(parent)
Defective phagocytic cell killing(parent)
Congenital immunodeficiency disease(parent)
Chronic disease of immune function(parent)
Hereditary disease(parent)
Chronic inflammatory disease(parent)
Quick Facts
- SNOMED CT
- 387759001
- UMLS CUI
- C0018203
- Fully Specified Name
- Chronic granulomatous disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 22
- Clinical Trials
- 7
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.