Common variable agammaglobulinemia

disorder

SNOMED 23238000CUI C0009447

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

B cell lymphopenia

Always present (100%)HP:0010976

Decreased class-switched memory B cell proportion

Always present (100%)HP:0030388

Decreased serum IgG

Always present (100%)HP:0004315

Low levels of immunoglobulin A

Always present (100%)HP:0002720

Prone to bacterial infection

Always present (100%)HP:0002718

Decreased circulating total IgM

Frequent (30-79%)HP:0002850

Neutropenia in presence of anti-neutropil antibodies

Occasional (5-29%)HP:0001904

Abnormal number of T cells

Excluded (<1%)HP:0011839

Bronchiectasis

HP:0002110

Bronchitis, recurrent

HP:0002837

Diarrhea

HP:0002014

Enlarged liver

HP:0002240

Immune deficiency

HP:0002721

Impaired T cell function

HP:0011840

Large spleen

Excluded (<1%)HP:0001744

Pink eye

HP:0000509

Pneumonia

HP:0002090

Pulmonary infections

HP:0006532

Recurrent middle ear infection

HP:0000403

Recurrent sinus infections

HP:0011108

Swollen lymph nodes

HP:0002716

Related Conditions

Hereditary neoplastic syndrome(parent)

Hereditary disorder of immune system(parent)

Common variable immunodeficiency(parent)

Quick Facts

SNOMED CT: 23238000
UMLS CUI: C0009447
Fully Specified Name: Common variable agammaglobulinemia (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 21

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.