Mikulicz's disease

disorder

SNOMED 7826003CUI C0026103

Overview

Mikulicz's disease is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abnormality of the salivary glands

Very frequent (80-99%)HP:0010286

Abnormality of the submandibular glands

Very frequent (80-99%)HP:0010287

Enlarged lacrimal glands

Very frequent (80-99%)HP:0007734

Increased circulating IgG4 level

Very frequent (80-99%)HP:0032300

Hyperplasia of parotid gland

Frequent (30-79%)HP:0011801

Abnormality of the extraocular muscles

Occasional (5-29%)HP:0008049

Abnormality of the orbital region

Occasional (5-29%)HP:0000315

Anti-neutrophil cytoplasmic antibody positivity

Occasional (5-29%)HP:0032230

Antinuclear antibodies

Occasional (5-29%)HP:0003493

Autoimmunity

Occasional (5-29%)HP:0002960

Facial swelling

Occasional (5-29%)HP:0000282

Fullness around the eyes

Occasional (5-29%)HP:0000629

Increased IgM levels

Occasional (5-29%)HP:0003496

Increased serum IgA

Occasional (5-29%)HP:0003261

Keratoconjunctivitis sicca

Occasional (5-29%)HP:0001097

Muscle inflammation

Occasional (5-29%)HP:0100614

Muscle weakness, generalised

Occasional (5-29%)HP:0003324

optic nerve abnormalities

Occasional (5-29%)HP:0000587

Prominent eyes

Occasional (5-29%)HP:0000520

Pyrexia

Occasional (5-29%)HP:0001945

Swelling of eyelids

Occasional (5-29%)HP:0100540

Tiredness

Occasional (5-29%)HP:0012378

Weight loss

Occasional (5-29%)HP:0001824

Xerostomia

Occasional (5-29%)HP:0000217

Abnormal lacrimal duct morphology

Very rare (1-4%)HP:0011481

Blindness

Very rare (1-4%)HP:0000618

Low platelet count

Very rare (1-4%)HP:0001873

Lymph node hyperplasia

Very rare (1-4%)HP:0002716

Nodular goiter

Very rare (1-4%)HP:0005994

Optic nerve compression

Very rare (1-4%)HP:0007807

Related Conditions

Disorder of lacrimal system(parent)

Disorder of salivary gland(parent)

Quick Facts

SNOMED CT: 7826003
UMLS CUI: C0026103
Fully Specified Name: Mikulicz's disease (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.