Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Bleeding tendency
Very frequent (80-99%)HP:0001892
Prolonged activated partial thromboplastin time
Very frequent (80-99%)HP:0003645
Reduced factor VIII activity
Very frequent (80-99%)HP:0003125
Arthritic pain
Frequent (30-79%)HP:0002829
Bleeding below the skin
Frequent (30-79%)HP:0001933
Bleeding gums
Frequent (30-79%)HP:0000225
Bleeding with minor or no trauma
Frequent (30-79%)HP:0011889
Intramuscular haematoma
Frequent (30-79%)HP:0012233
Joint hemorrhage
Frequent (30-79%)HP:0005261
Cartilage destruction
Occasional (5-29%)HP:0100773
Disease of the joints
Occasional (5-29%)HP:0003040
Gastrointestinal haemorrhage
Occasional (5-29%)HP:0002239
Headache
Occasional (5-29%)HP:0002315
High urine occult blood
Occasional (5-29%)HP:0000790
Intracranial haemorrhage
Occasional (5-29%)HP:0002170
Joint swelling
Occasional (5-29%)HP:0001386
Limitation of joint mobility
Occasional (5-29%)HP:0001376
Prolonged bleeding after dental extraction
Occasional (5-29%)HP:0006298
Protracted bleeding after surgery
Occasional (5-29%)HP:0004846
Subdural haematoma
Occasional (5-29%)HP:0100309
Synovitis
Occasional (5-29%)HP:0100769
Epidural hematoma
Very rare (1-4%)HP:0100310
Flexion contractures of hips
Very rare (1-4%)HP:0003273
Intraventricular hemorrhage
Very rare (1-4%)HP:0030746
Seizures
Very rare (1-4%)HP:0001250
Spontaneous hematomas
Very rare (1-4%)HP:0007420
Related Conditions
Quick Facts
- SNOMED CT
- 33344008
- UMLS CUI
- C0272323
- Fully Specified Name
- Moderate hereditary factor VIII deficiency disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 26
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.