Selective IgM immunodeficiency

disorder

SNOMED 190980000CUI C0154275

Overview

Selective IgM immunodeficiency is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Decreased circulating total IgM

Very frequent (80-99%)HP:0002850

respiratory infections, recurrent

Very frequent (80-99%)HP:0002205

Susceptibility to infection

Very frequent (80-99%)HP:0002719

Unusual course of infection

Very frequent (80-99%)HP:0032169

Allergy

Frequent (30-79%)HP:0012393

Autoimmune disorder

Frequent (30-79%)HP:0002960

Decreased specific antibody response to vaccination

Frequent (30-79%)HP:0032140

Multiple pulmonary infections

Frequent (30-79%)HP:0006532

Recurrent sinus disease

Frequent (30-79%)HP:0011108

Recurrent URI

Frequent (30-79%)HP:0002788

Antinuclear antibodies

Occasional (5-29%)HP:0003493

Bronchiectasis

Occasional (5-29%)HP:0002110

Bronchitis, recurrent

Occasional (5-29%)HP:0002837

Chronic diarrhoea

Occasional (5-29%)HP:0002028

Chronic extreme exhaustion

Occasional (5-29%)HP:0012432

Chronic oral thrush

Occasional (5-29%)HP:0009098

Corneal inflammation

Occasional (5-29%)HP:0000491

Decreased proportion of CD19+CD38+IgM+ cells

Occasional (5-29%)HP:0030380

Decreased proportion of CD4-positive T cells

Occasional (5-29%)HP:0032218

Hay fever

Occasional (5-29%)HP:0003193

Idiopathic thrombocytopenia

Occasional (5-29%)HP:0001973

Infection in blood stream

Occasional (5-29%)HP:0100806

Meningitis

Occasional (5-29%)HP:0001287

Neutropenia in presence of anti-neutropil antibodies

Occasional (5-29%)HP:0001904

Non-infectious meningitis

Occasional (5-29%)HP:0033430

Nontuberculous mycobacterial pulmonary infection

Occasional (5-29%)HP:0032261

Otitis media

Occasional (5-29%)HP:0000388

Paraproteinemia

Occasional (5-29%)HP:0031047

Pharyngitis

Occasional (5-29%)HP:0025439

Prurigo Besnier

Occasional (5-29%)HP:0001047

Related Conditions

Immunoglobulin heavy chain deficiency(parent)

Quick Facts

SNOMED CT: 190980000
UMLS CUI: C0154275
Fully Specified Name: Selective immunoglobulin M deficiency (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.