Substance / Medication

125-I

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Transarterial chemoembolization with 125 I seed insertion for unresectable hepatocellular carcinoma: a meta‑analysis.
Zhu Rui, Mao Kui, Lu Xin-Zhi et al. · Wideochir Inne Tech Maloinwazyjne · 2025
PMID: 40547831Meta-AnalysisFull text (PMC)
Implantation of radioactive (125)I seeds improves the prognosis of locally advanced pancreatic cancer patients: A retrospective study.
Li Yong-Feng, Liu Zhi-Qiang, Zhang Yu-Shun et al. · J Huazhong Univ Sci Technolog Med Sci · 2016
PMID: 27072963RCT
[Application of neoadjuvant hormonal therapy in (125)I permanent seed implantation for prostate cancer].
Cui Xin, Li Qiang, Xu Jian-jun et al. · Zhonghua Yi Xue Za Zhi · 2012
PMID: 23290112RCT
[Operation combined with (125)I radioactive seeds implantation therapy on advanced esophageal squamous cell carcinoma].
Lü Jin, Cao Xiu-feng, Zhu Bin et al. · Zhonghua Wai Ke Za Zhi · 2010
PMID: 20450603RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Iodine-125 (substance)
SNOMED CT
68630002
UMLS CUI
C0796396

Clinical Data

This intervention maps to 6 entities in the Ltrl knowledge graph.

6
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.