Substance / Medication

Amantadine sulfate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
[The use of amantadine sulfate in ischemic stroke].
Ramazanov G R, Kovaleva E A, Shevchenko E V et al. · Zh Nevrol Psikhiatr Im S S Korsakova · 2020
PMID: 33449534RCT
[Amantadine sulfate (PK-Merz) in the treatment of ischemic stroke: a clinical-experimental study].
Khasanova D R, Saĭkhunov M V, Kitaeva E A et al. · Zh Nevrol Psikhiatr Im S S Korsakova · 2009
PMID: 19894299Observational
Amantadine sulfate reduces experimental sensitization and pain in chronic back pain patients.
Kleinböhl Dieter, Görtelmeyer Roman, Bender Hans-Joachim et al. · Anesth Analg · 2006
PMID: 16492838Observational
[Results of treatment with intravenous amantadine sulfate (PK-Merz) patients with chronic disorders of consciousness].
Kondratieva E A, Kondratev S A, Denisova A A et al. · Zh Nevrol Psikhiatr Im S S Korsakova · 2020
PMID: 33459549Other
[Clinical and electroencephalographic effects of amantadine sulfate (PK-Merz) on consciousness disorders due to the severe traumatic brain injury].
Cheliapina M V, Sharova E V, Zaĭtsev O S · Zh Nevrol Psikhiatr Im S S Korsakova · 2011
PMID: 21666589Other
[The effect of amantadine sulfate on cognitive disorders in patients with Parkinson's disease].
Iablonskaia A Iu, Fedorova N V, Bel'gusheva M E · Zh Nevrol Psikhiatr Im S S Korsakova · 2010
PMID: 20639853Other
[The use of amantadine sulfate in combined therapy of Parkinson's disease].
Karaban' I N, Lukhanina E P, Kapustina M T et al. · Zh Nevrol Psikhiatr Im S S Korsakova · 2002
PMID: 12161861Other
Movement disorder in ataxia-telangiectasia: treatment with amantadine sulfate.
Nissenkorn Andreea, Hassin-Baer Sharon, Lerman Sheera F et al. · J Child Neurol · 2013
PMID: 22550086Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Amantadine sulfate (substance)
SNOMED CT
703084004
UMLS CUI
C0002404

Clinical Data

This intervention maps to 6 entities in the Healos knowledge graph.

6
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.