Substance / Medication

Chlorhexidine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

3 trials linked to this intervention

3
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Evaluation of the antifungal effect of plant extracts on oralspp. - a critical methodological analysis of the last decade.
Maziere M, Andrade J C, Rompante P et al. · Crit Rev Microbiol · 2025
PMID: 38497208Meta-Analysis
Comparative efficacy of antifungal drugs for the treatment of oral candidiasis in HIV-positive patients: A Bayesian network meta-analysis.
Lin Jiong, Peng Cai-Xia, Huang Wei-Man · Med Clin (Barc) · 2025
PMID: 39214731Meta-Analysis
Oral Candida-biome and Early Childhood Caries: A Systematic Review and Meta-Analysis.
Man Vanessa C W, Manchanda Sheetal, Yiu Cynthia Ky · Int Dent J · 2025
PMID: 39322518Meta-AnalysisFull text (PMC)
Efficacy of probiotics for oral candidiasis management: a systematic review.
Li Pengjin, Yu Xizhe, Chen Chen et al. · BMC Oral Health · 2025
PMID: 40604878Meta-AnalysisFull text (PMC)
Oral Candida in Orthodontic Patients Wearing Removable Orthodontic Appliances: A Systematic Review and Meta-Analysis.
Siripaisanprasert Kreaukarn, Prapinjumrune Chanwit, Changsiripun Chidsanu · Int Dent J · 2025
PMID: 40675004Meta-AnalysisFull text (PMC)
Are Candida albicans isolates from people living with HIV more resistant to antifungals? A systematic review and meta-analysis.
Costacurta Maria Rita Rodon, Orlandini Renata Klemp, Rocha Amanda Carolina de Souza Delfino da et al. · Microb Pathog · 2025
PMID: 40675507Meta-Analysis
Bimekizumab safety in patients with moderate-to-severe plaque psoriasis: pooled data from up to 3 years of treatment in randomized phase III trials.
Gordon Kenneth B, Langley Richard G, Warren Richard B et al. · Br J Dermatol · 2024
PMID: 37950894Meta-Analysis
Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy onspp.-A Systematic Review.
Kubizna Magdalena, Dawiec Grzegorz, Wiench Rafał · Int J Mol Sci · 2024
PMID: 39125706Meta-AnalysisFull text (PMC)
Evaluation of chlorhexidine hydrochloride treatment on endometrial health of normal mares.
Fraser Natalie S, Johnson Aime K, Wilborn Robyn R et al. · Theriogenology · 2017
PMID: 27865413RCT
Synergistic activity of tetrasodium EDTA, ethanol and chlorhexidine hydrochloride against planktonic and biofilm cells of clinically relevant pathogens.
Sivaranjani Murugesan, Liu Fangning, White Aaron P · J Glob Antimicrob Resist · 2021
PMID: 33383260Other

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Chlorhexidine hydrochloride (substance)
SNOMED CT
96318003
UMLS CUI
C0008199

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
3
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.