Substance / Medication

Clioquinol

Overview

Active Ingredient
clioquinol
RxNorm CUI
5942

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

3 trials linked to this intervention

3
Total Trials
0
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Clioquinol for the treatment of Alzheimer's Disease.
Jenagaratnam L, McShane R · Cochrane Database Syst Rev · 2006
PMID: 16437529Meta-Analysis
Novel spectrophotometric determination of flumethasone pivalate and clioquinol in their binary mixture and pharmaceutical formulation.
Abdel-Aleem Eglal A, Hegazy Maha A, Sayed Nour W et al. · Spectrochim Acta A Mol Biomol Spectrosc · 2015
PMID: 25448970Observational
Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline).
Jiang Hongchao, Taggart Jori E, Zhang Xiaoxi et al. · Cancer Lett · 2011
PMID: 21899946ObservationalFull text (PMC)
The metal chelating and chaperoning effects of clioquinol: insights from yeast studies.
Li Chenghua, Wang Juan, Zhou Bing · J Alzheimers Dis · 2010
PMID: 21504115Observational
Clinical analysis of longstanding subacute myelo-optico-neuropathy: sequelae of clioquinol at 32 years after its ban.
Konagaya Masaaki, Matsumoto Akihisa, Takase Sadao et al. · J Neurol Sci · 2004
PMID: 14759638Observational
Clioquinol effects on tissue chelatable zinc in mice.
Nitzan Yuval B, Sekler Israel, Frederickson Christopher J et al. · J Mol Med (Berl) · 2003
PMID: 12928783Observational
Clioquinol treatment in familiar early onset of Alzheimer's disease: a case report.
Ibach B, Haen E, Marienhagen J et al. · Pharmacopsychiatry · 2005
PMID: 16025421Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Clioquinol (substance)
SNOMED CT
387291001
UMLS CUI
C0021978
RxNorm CUI
5942

Clinical Data

This intervention maps to 3 entities in the Healos knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
3
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.