Substance / Medication

Clomiphene

Overview

Active Ingredient
clomiphene
RxNorm CUI
2596

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

9 trials linked to this intervention

9
Total Trials
1
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Clomiphene or enclomiphene citrate for the treatment of male hypogonadism: a systematic review and meta-analysis of randomized controlled trials.
Hohl Alexandre, Chavez Matheus Pedrotti, Pasqualotto Eric et al. · Arch Endocrinol Metab · 2025
PMID: 41066380Meta-AnalysisFull text (PMC)
Letrozole and clomiphene versus letrozole alone for ovulation induction in women with PCOS: a systematic review and meta-analysis.
Eskandar Karine, Oliveira Juliana Almeida, Ribeiro Sandro Augusto et al. · Rev Bras Ginecol Obstet · 2025
PMID: 40406474Meta-AnalysisFull text (PMC)
Effects of letrozole combined with clomiphene in the treatment of polycystic ovary syndrome: a meta-analysis.
Du Baoying, Ni Mengdi, Chen Ping · BMC Womens Health · 2025
PMID: 40660210Meta-AnalysisFull text (PMC)
A meta-analysis of efficacy on dexamethasone and clomiphene in the treatment of polycystic ovary syndrome patients.
Sha Ying, Zhu Jianfen, Shen Fangrong · BMC Womens Health · 2024
PMID: 38769509Meta-AnalysisFull text (PMC)
Comparison of Letrozole and Clomiphene Citrate in Pregnancy Outcomes in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis.
Abu-Zaid Ahmed, Gari Abdulrahim, Sabban Hussein et al. · Reprod Sci · 2024
PMID: 38030814Meta-Analysis
Is combined letrozole and clomiphene superior to either as monotherapy: a systemic review and meta-analysis based on clinical trials.
Ashkar Anusha, Jadoon Bismeen, Ali Baig Mirza Mehmood et al. · Gynecol Endocrinol · 2024
PMID: 39297798Meta-Analysis
Letrozole Compared With Clomiphene Citrate for Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis.
Liu Zhuo, Geng Yuli, Huang Yanjing et al. · Obstet Gynecol · 2023
PMID: 36735392Meta-Analysis
Clomiphene citrate for male infertility: A systematic review and meta-analysis.
Huijben Manou, Huijsmans Roel L N, Lock M Tycho W T et al. · Andrology · 2023
PMID: 36680549Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Clomifene (substance)
SNOMED CT
387166005
UMLS CUI
C0009008
RxNorm CUI
2596

Clinical Data

This intervention maps to 9 entities in the Healos knowledge graph.

2
Conditions
3
Biomarkers
3
Specialists
0
Symptoms
9
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.