Estradiol
Measures estradiol hormone levels in saliva.
Why This Biomarker Matters
Estradiol balance is crucial for bone health, mood, sexual function, and cardiovascular health. Salivary testing provides insight into active hormone levels and helps optimize hormone therapy or identify imbalances.
Understanding Your Results
Normal Range
0.1 – 1.5 pg/mL
Optimal Ranges
Clinician-defined 4-point reference thresholds (pg/mL)
male — Default Range
Overview
Estradiol is the primary estrogen hormone in the body, measured through saliva. Salivary estradiol reflects biologically active hormone levels and is useful for tracking hormonal changes throughout the menstrual cycle, during perimenopause, or with hormone therapy. Abnormal estradiol levels can affect mood, bone health, sexual function, and cardiovascular risk. This non-invasive test helps assess hormone balance and guide treatment decisions.
Related Health Conditions
Conditions where Estradiol is commonly tested
Related Health Goals
Treatments & Interventions
Therapies monitored using Estradiol
Progesterone
Testosterone
Bromocriptine mesylate
Estrone
Human chorionic gonadotropin
Estrogen receptor agonist-containing product
Testosterone propionate
Estradiol benzoate
Estradiol valerate
Estradiol cypionate
Testosterone cypionate
Estradiol hemihydrate
Testosterone enanthate
Polyestradiol phosphate
Ethinylestradiol
Clinical Trials
Recent Trials
Adaptions and Resiliency to Multi-Stressor OpeRations
52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism
Determining Dose Equivalence Between Oral and Transdermal Estrogen Treatment in Women With Turner Syndrome
Long Term Effects of Oral Versus Transdermal Estrogen Replacement Therapy in Turner Syndrome
A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months
Research & Evidence
8 publications
Research data from MEDLINE/PubMed · 8 articles
Technical Information (LOINC Codes)
Standardized laboratory codes for this biomarker
2243-4Primary35384-72238-414715-783096-831176-134286-534287-355857-755858-572873-383097-697741-312595-597742-121263-92239-22245-925401-1Available Lab Tests
Order tests that measure this biomarker
Find Specialists
Doctors who commonly order this test