← Back to Conditions

Hypogonadism

disorder

SNOMED 48130008CUI C0020619

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Specialists & Providers

Endocrinology, Diabetes & Metabolism Physician

Internal Medicine — Endocrinology, Diabetes & Metabolism

Urology Physician

Urology

Diagnostic Biomarkers

Thyrotropin

3016-3secondary

Estradiol

Testosterone

Clinical Trials

52

Total Trials

6

Recruiting

16

With Results

Recent Trials

Adaptions and Resiliency to Multi-Stressor OpeRations

NCT06455969Phase 4Recruiting120 enrolled

52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

NCT06689085Phase 3Recruiting100 enrolled

Long Term Effects of Oral Versus Transdermal Estrogen Replacement Therapy in Turner Syndrome

NCT06570460Phase 4Recruiting50 enrolled

Determining Dose Equivalence Between Oral and Transdermal Estrogen Treatment in Women With Turner Syndrome

NCT06544473Phase 4Recruiting50 enrolled

A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months

NCT06385509Phase 4Active Not Recruiting110 enrolled

View all 52 trials on ClinicalTrials.gov

Research Evidence

Peer-reviewed studies linked via MeSH term "Hypogonadism" from the MEDLINE/PubMed database.

Sort:

Reversal of Congenital Hypogonadotropic Hypogonadism.

[object Object], [object Object] · J Clin Endocrinol Metab · 2026

PMID: 41206002Meta-AnalysisFull text (PMC)

Incomplete Evidence of Bone Density Normalization Following Long-Term Reproductive Hormone Treatment in Men With Hypogonadotropic Hypogonadism.

[object Object], [object Object], [object Object] et al. · J Clin Endocrinol Metab · 2025

PMID: 41032457Meta-AnalysisFull text (PMC)

Efficacy and Safety of Testosterone Replacement in Testicular Cancer Survivors With Treatment-Influenced Hypogonadism: A Systematic Review.

[object Object], [object Object] · Ann Pharmacother · 2025

PMID: 39250190Meta-Analysis

Effects of glucagon-like peptide 1 receptor agonists on testicular dysfunction: A systematic review and meta-analysis.

[object Object], [object Object], [object Object] et al. · Andrology · 2025

PMID: 40105090Meta-AnalysisFull text (PMC)

Long-Term Cardiovascular Safety of Testosterone-Replacement Therapy in Middle-Aged and Older Men: A Meta-analysis of Randomized Controlled Trials.

[object Object], [object Object], [object Object] et al. · Am J Cardiovasc Drugs · 2025

PMID: 40694252Meta-Analysis

Oncological safety of testosterone replacement therapy in men with localised prostate cancer: a systematic review of observational studies.

[object Object], [object Object], [object Object] et al. · BJU Int · 2025

PMID: 40747831Meta-Analysis

Gonadotropin Therapy for Mini-Puberty Induction in Male Infants With Hypogonadotropic Hypogonadism.

[object Object], [object Object], [object Object] et al. · J Clin Endocrinol Metab · 2025

PMID: 39673783Meta-AnalysisFull text (PMC)

Efficacy of Gonadotropin Treatment for Induction of Spermatogenesis in Men With Pathologic Gonadotropin Deficiency: A Meta-Analysis.

[object Object], [object Object], [object Object] et al. · Clin Endocrinol (Oxf) · 2025

PMID: 39445789Meta-Analysis

Clinical presentation of congenital hypogonadotropic hypogonadism in males with delayed puberty according to genetic etiology: a systematic review and meta-analysis after reclassification of gene variants.

[object Object], [object Object], [object Object] et al. · Hum Reprod · 2025

PMID: 40101754Meta-Analysis

Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men.

[object Object], [object Object], [object Object] et al. · Nat Commun · 2025

PMID: 40316537Meta-AnalysisFull text (PMC)

Search all PubMed articles for Hypogonadism

Research data from MEDLINE/PubMed

Related Conditions

Female hypogonadism syndrome(child)

Hypogonadotropic hypogonadism(child)

Male hypogonadism(child)

Hypogonadal obesity(child)

Gonad postablative failure(child)

Primary hypogonadism(child)

Congenital muscular dystrophy with infantile cataract and hypogonadism syndrome(child)

Deafness and hypogonadism syndrome(child)

Syndromic X-linked intellectual disability type 7(child)

Intellectual disability, balding, patella luxation, acromicria syndrome(child)

Congenital cataract with deafness and hypogonadism syndrome(child)

Retinitis pigmentosa, intellectual disability, deafness, hypogenitalism syndrome(child)

Frontonasal dysplasia with alopecia and genital anomaly syndrome(child)

Microcephalic primordial dwarfism, insulin resistance syndrome(child)

Juvenile hemochromatosis(child)

Disorder of endocrine gonad(parent)

Quick Facts

SNOMED CT: 48130008
UMLS CUI: C0020619
Fully Specified Name: Hypogonadism (disorder)
Specialists: 2
Diagnostic Biomarkers: 3
Known Treatments: 20
Clinical Trials: 52

Related Health Goals

Balance Hormones

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.