Substance / Medication

Cobalamin

Overview

Active Ingredient
vitamin B12
RxNorm CUI
11248

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Ocular manifestations in patients with inborn errors of intracellular cobalamin metabolism: a systematic review.
Matmat Karim, Guéant-Rodriguez Rosa-Maria, Oussalah Abderrahim et al. · Hum Genet · 2022
PMID: 34652574Meta-Analysis
The Relationship of Cobalamin and/or Folate to the Patient-Centred Outcomes in Multiple Sclerosis: A Systematic Review and Meta-analysis.
Kirsty Cummins-Williams, Mary Hickson, Sumner Jonathan · Nutr Health · 2022
PMID: 35254171Meta-Analysis
Pyridoxine, folate and cobalamin for migraine: A systematic review.
Liampas Ioannis N, Siokas Vasileios, Aloizou Athina-Maria et al. · Acta Neurol Scand · 2020
PMID: 32279306Meta-Analysis
Cobalamin deficiency presenting with thrombotic microangiopathy (TMA) features: A systematic review.
Tran Phu Ngoc, Tran Minh-Ha · Transfus Apher Sci · 2018
PMID: 29454538Meta-Analysis
Efficacy of oral cobalamin (vitamin B12) therapy.
Andrès Emmanuel, Fothergill Helen, Mecili Mustapha · Expert Opin Pharmacother · 2010
PMID: 20088746Meta-Analysis
Oral cobalamin (vitamin B(12)) treatment. An update.
Andrès E, Dali-Youcef N, Vogel T et al. · Int J Lab Hematol · 2009
PMID: 19032377Meta-Analysis
Serum cobalamin in children with moderate acute malnutrition in Burkina Faso: Secondary analysis of a randomized trial.
Friis Henrik, Cichon Bernardette, Fabiansen Christian et al. · PLoS Med · 2022
PMID: 35263343RCTFull text (PMC)
Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal.
Schwinger Catherine, Sharma Shakun, Chandyo Ram K et al. · J Nutr Sci · 2021
PMID: 34422259RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cobalamin (substance)
SNOMED CT
304111003
UMLS CUI
C0042845
RxNorm CUI
11248

Clinical Data

This intervention maps to 9 entities in the Ltrl knowledge graph.

4
Conditions
3
Biomarkers
1
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.