Substance / Medication

Emetine

Overview

Active Ingredient
emetine
RxNorm CUI
3820

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma.
Kong Hye-Sik, Lee Sunmin, Beebe Kristin et al. · Mol Pharmacol · 2010
PMID: 20813864ObservationalFull text (PMC)
[Effect of intralesional treatment with emetine hydrochloride on Leishmania (Viannia) braziliensis in hamsters].
Cazorla D, Yépez J, Añez N et al. · Invest Clin · 2001
PMID: 11294031Observational
Emetine: Advances in Pharmacology, Toxicology, and Chromatographic Approaches.
Gebrehiwot Weldejeworgis, Tok Kenan Can, Alkhashi Jamilah S et al. · Crit Rev Anal Chem · 2025
PMID: 40660855Review
Spectroscopic Investigation of Emetine-DNA Binding.
Udeochu Uche, Smith Carin, Kong Srey et al. · J Med Chem · 2025
PMID: 41276992Other
The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Eiler Daniel R, Wimberly Brian T, Bilodeau Danielle Y et al. · Structure · 2024
PMID: 38242118OtherFull text (PMC)
Emetine induces oxidative stress, cell differentiation and NF-κB inhibition, suppressing AML stem/progenitor cells.
Silva Suellen L R, Dias Ingrid R S B, Rodrigues Ana Carolina B da C et al. · Cell Death Discov · 2024
PMID: 38684672OtherFull text (PMC)
Alkaloids (emetine and cephalin) production - affected by full sunlight stress in.
Moll Hüther Cristina, Ferreira Vitor Francisco, de Carvalho da Silva Fernando et al. · Nat Prod Res · 2024
PMID: 36787159Other
Liposomes loaded with daunorubicin and an emetine prodrug for improved selective cytotoxicity towards acute myeloid leukaemia cells.
Reiten Ingeborg Nerbø, Giraud Francis, Augedal Tuva Torblå et al. · Int J Pharm · 2025
PMID: 39581514Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Emetine (substance)
SNOMED CT
373466009
UMLS CUI
C0013974
RxNorm CUI
3820

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.