Substance / Medication

Linolenic acid

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

53 trials linked to this intervention

53
Total Trials
7
Recruiting
12
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Metabolic, structure-activity characteristics of conjugated linolenic acids and their mediated health benefits.
Du Meijun, Jin Jun, Wu Gangcheng et al. · Crit Rev Food Sci Nutr · 2024
PMID: 37021469Meta-Analysis
Effects of supplementation with vegetable sources of alpha-linolenic acid (ALA) on inflammatory markers and lipid profile in individuals with chronic kidney disease: A systematic review and meta-analysis.
de Abreu Aline Miroski, Copetti Cândice Laís Knöner, Hauschild Daniela Barbieri et al. · Clin Nutr · 2022
PMID: 35341608Meta-Analysis
Impact of α-Linolenic Acid, the Vegetable ω-3 Fatty Acid, on Cardiovascular Disease and Cognition.
Sala-Vila Aleix, Fleming Jennifer, Kris-Etherton Penny et al. · Adv Nutr · 2022
PMID: 35170723Meta-AnalysisFull text (PMC)
Dietary Intake and Biomarkers of α-Linolenic Acid and Mortality: A Meta-Analysis of Prospective Cohort Studies.
Chen Li-Hua, Hu Qingjing, Li Guijie et al. · Front Nutr · 2021
PMID: 34805241Meta-AnalysisFull text (PMC)
α-Linolenic Acid and Risk of Heart Failure: A Meta-Analysis.
Wu Jiandi, Qiu Min, Sun Lichang et al. · Front Cardiovasc Med · 2021
PMID: 35059448Meta-AnalysisFull text (PMC)
Effects of α-linolenic acid intake on blood lipid profiles:a systematic review and meta-analysis of randomized controlled trials.
Yue Hao, Qiu Bin, Jia Min et al. · Crit Rev Food Sci Nutr · 2021
PMID: 32643951Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Linolenic acid (substance)
SNOMED CT
81868000
UMLS CUI
C0125903

Clinical Data

This intervention maps to 10 entities in the Ltrl knowledge graph.

2
Conditions
3
Biomarkers
3
Specialists
0
Symptoms
53
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.