Substance / Medication

Magnesium

Overview

Active Ingredient
magnesium
RxNorm CUI
6574

Indications

® VitafolOne is indicated to provide vitamin, mineral, and omega-3 fatty acid supplementation prior to conception, throughout pregnancy, and during the postnatal period for the lactating and non-lactating mother, including individuals with known allergies to fish.*

Labeler: Exeltis USA, Inc.Updated: 2025-03-20T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or a Poison Control Center immediately.

Contraindications

When this intervention should not be used

® VitafolOne is contraindicated in patients with hypersensitivity to any of its components or color additives. Folic acid is contraindicated in patients with untreated and uncomplicated pernicious anemia, and in those with anaphylactic sensitivity to folic acid. Iron therapy is contraindicated in

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

18 trials linked to this intervention

18
Total Trials
2
Recruiting
6
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Calcium, magnesium, and vitamin D supplementations as complementary therapy for hypertensive patients: a systematic review and meta-analysis.
Amer Samar A, Abo-Elnour Dina Essam, Abbas Abdallah et al. · BMC Complement Med Ther · 2025
PMID: 40045266Meta-AnalysisFull text (PMC)
Magnesium Alterations in Human Spaceflight.
Diaz Thomas E, Sullivan Ryan D, Ashworth Edward T et al. · Aerosp Med Hum Perform · 2025
PMID: 41043820Meta-Analysis
Does Magnesium Affect Sex Hormones and Cardiometabolic Risk Factors in Patients with PCOS? Findings from a Systematic Review and Meta-Analysis.
Abu-Zaid Ahmed, Alzayed Mooza M, Albahrani Suha Jafar et al. · Medicina (Kaunas) · 2025
PMID: 40005397Meta-AnalysisFull text (PMC)
Does Magnesium Provide a Protective Effect in Crohn's Disease Remission? A Systematic Review of the Literature.
Costescu Sergiu, Bratosin Felix, Popa Zoran Laurentiu et al. · Nutrients · 2024
PMID: 38892595Meta-AnalysisFull text (PMC)
Associations Between Serum Magnesium Concentrations and Polycystic Ovary Syndrome Status: a Systematic Review and Meta-analysis.
Babapour Maedeh, Mohammadi Hamed, Kazemi Maryam et al. · Biol Trace Elem Res · 2021
PMID: 32812171Meta-Analysis
Association between magnesium concentrations and prediabetes: a systematic review and meta-analysis.
Ebrahimi Mousavi Sara, Ghoreishy Seyed Mojtaba, Hemmati Amirhossein et al. · Sci Rep · 2021
PMID: 34937856Meta-AnalysisFull text (PMC)
Magnesium status and attention deficit hyperactivity disorder (ADHD): A meta-analysis.
Effatpanah Mohammad, Rezaei Mahdi, Effatpanah Hosein et al. · Psychiatry Res · 2019
PMID: 30807974Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Magnesium (substance)
SNOMED CT
72717003
UMLS CUI
C0024467
RxNorm CUI
6574
Labeler
Exeltis USA, Inc.

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

1
Conditions
1
Biomarkers
0
Specialists
0
Symptoms
18
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.