Substance / Medication

Mefloquine

Overview

Active Ingredient
mefloquine
RxNorm CUI
6694

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

6 trials linked to this intervention

6
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Artesunate-mefloquine therapy for uncomplicated Plasmodium falciparum malaria: an updated systematic review and meta-analysis of efficacy and safety.
de Freitas Beatriz Sales, Fernandes Gabriel Haiek, Pereira Ana Carolina Esteves da Silva et al. · Trans R Soc Trop Med Hyg · 2024
PMID: 37772768Meta-Analysis
Mefloquine for preventing malaria in pregnant women.
González Raquel, Pons-Duran Clara, Piqueras Mireia et al. · Cochrane Database Syst Rev · 2018
PMID: 29561063Meta-AnalysisFull text (PMC)
Mefloquine for preventing malaria in pregnant women.
González Raquel, Pons-Duran Clara, Piqueras Mireia et al. · Cochrane Database Syst Rev · 2018
PMID: 30480761Meta-AnalysisFull text (PMC)
Mefloquine for preventing malaria during travel to endemic areas.
Tickell-Painter Maya, Maayan Nicola, Saunders Rachel et al. · Cochrane Database Syst Rev · 2017
PMID: 29083100Meta-AnalysisFull text (PMC)
Mefloquine safety and tolerability in pregnancy: a systematic literature review.
González Raquel, Hellgren Urban, Greenwood Brian et al. · Malar J · 2014
PMID: 24581338Meta-AnalysisFull text (PMC)
WITHDRAWN: Mefloquine for preventing malaria in non-immune adult travellers.
Croft A M J, Garner P · Cochrane Database Syst Rev · 2008
PMID: 18253969Meta-AnalysisFull text (PMC)
Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria.
Bukirwa H, Orton L · Cochrane Database Syst Rev · 2005
PMID: 16235367Meta-AnalysisFull text (PMC)
Mefloquine for preventing malaria in non-immune adult travellers.
Croft A M, Garner P · Cochrane Database Syst Rev · 2000
PMID: 11034675Meta-Analysis
Mefloquine for preventing malaria in non-immune adult travellers.
Croft A M, Garner P · Cochrane Database Syst Rev · 2000
PMID: 10796493Meta-Analysis
Mefloquine for preventing malaria in non-immune adult travellers.
Croft A M, Garner P · Cochrane Database Syst Rev · 2000
PMID: 10908460Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Mefloquine (substance)
SNOMED CT
387505001
UMLS CUI
C0025153
RxNorm CUI
6694

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
6
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.