Substance / Medication

Methylprednisolone

Overview

Active Ingredient
methylprednisolone
RxNorm CUI
6902

Indications

Methylprednisolone tablets are indicated in the following conditions:

Labeler: NuCare Pharmaceuticals,Inc.Updated: 2026-02-20T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Systemic fungal infections and known hypersensitivity to components.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

464 trials linked to this intervention

464
Total Trials
78
Recruiting
138
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of various Intravenous Methylprednisolone regimens in Moderate to Severe Thyroid Eye Disease: A systematic review.
Aishwarya Ankita, Shrivastava Divanshi, Singh Adarsh Kumar et al. · Indian J Ophthalmol · 2025
PMID: 40719710Meta-AnalysisFull text (PMC)
The use of methylprednisolone after third molar surgery. A systematic review and meta-analysis of randomized controlled trials.
Libório H, Borges T, Pereira M et al. · Med Oral Patol Oral Cir Bucal · 2025
PMID: 39724528Meta-AnalysisFull text (PMC)
The Efficacy, Adverse Effects and Economic Implications of Oral Versus Intravenous Methylprednisolone for the Treatment of Optic Neuritis: A Systematic Review.
Pietris James, Lam Antoinette, Bacchi Stephen et al. · Semin Ophthalmol · 2024
PMID: 38013424Meta-Analysis
The role of methylprednisolone in severe COVID-19 patients: a meta-analysis.
Xu Wanru, Zeng Yujun, Han Hedong et al. · Front Med (Lausanne) · 2024
PMID: 39185470Meta-AnalysisFull text (PMC)
Efficacy of Preemptive Dexamethasone versus Methylprednisolone in the Management of Postoperative Discomfort and Pain after Mandibular Third Molar Surgery: A Systematic Review and Meta-Analysis.
Singh Anupam, Pentapati Kalyana Chakravarthy, Kodali Murali Venkata Rama Mohan et al. · ScientificWorldJournal · 2023
PMID: 37168455Meta-AnalysisFull text (PMC)
A systematic review and meta-analysis of glucocorticoids treatment in severe COVID-19: methylprednisolone versus dexamethasone.
Hong Shukun, Wang Hongye, Li Shuyuan et al. · BMC Infect Dis · 2023
PMID: 37147596Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Methylprednisolone (substance)
SNOMED CT
116593003
UMLS CUI
C0025815
RxNorm CUI
6902
Labeler
NuCare Pharmaceuticals,Inc.

Clinical Data

This intervention maps to 36 entities in the Healos knowledge graph.

20
Conditions
7
Biomarkers
6
Specialists
0
Symptoms
464
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.