Substance / Medication

Nafarelin acetate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Experiences of pain communication in endometriosis: A meta-synthesis.
Robstad Nastasja, Paulsen Anita, Vistad Ingvild et al. · Acta Obstet Gynecol Scand · 2025
PMID: 39440568Meta-AnalysisFull text (PMC)
Childhood adversity and risk of endometriosis, fibroids, and polycystic ovary syndrome: a systematic review.
Berndt Sara L, Ribeiro Leticia Watanabe, Rowlands Ingrid et al. · Fertil Steril · 2025
PMID: 39521113Meta-Analysis
Effects of anti-inflammatory dietary supplements on pelvic pain in females with endometriosis: A GRADE-assessed systematic review and meta-analysis of RCTs.
Naeini Fatemeh, Tanha Fatemeh Davari, Ansar Hastimansooreh et al. · Int J Gynaecol Obstet · 2025
PMID: 39692186Meta-Analysis
Dyspareunia is rarely assessed in rodent models of endometriosis and interstitial cystitis/bladder pain syndrome.
Nunez-Badinez Paulina, Shah Razneen, Demetriou Lysia et al. · Reprod Fertil · 2025
PMID: 39704692Meta-AnalysisFull text (PMC)
Dose of GnRH agonist (nafarelin acetate) affects intrafollicular PAPP-A expression in controlled ovarian hyperstimulation cycle.
Suh JiHyun, Lee EunYoung, Hwang SeongSoo et al. · Eur J Obstet Gynecol Reprod Biol · 2004
PMID: 14687742Observational
Crohn's disease mimicking as bowel endometriosis. Are the symptoms reduced by nafarelin acetate?
Nakao A, Iwagaki H, Kanagawa T et al. · Arch Gynecol Obstet · 2000
PMID: 10763842Case Report
[Nafarelin acetate (Synarel) and thermocoagulation in the treatment of endometriosis].
Palatyński A, Gruszczyńska J, Sobkiewicz S · Ginekol Pol · 2001
PMID: 11526758Trial
[Treatment of pelvic endometriosis with goserelin acetate or nafarelin acetate. Comparative study].
Calvo Lugo G E, Sauceda González L F, Jiménez Perea M L et al. · Ginecol Obstet Mex · 2000
PMID: 10774095Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Nafarelin acetate (substance)
SNOMED CT
109047000
UMLS CUI
C0700477

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.