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Substance / Medication

Pancreatin

SNOMED 387049005UMLS C0030304

Overview

Active Ingredient
pancreatin
RxNorm CUI
7880

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Disorder of gastrointestinal tract

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
0
Recruiting
0
With Results

Recent Trials

Gastrectomy Study: Study to Investigate the Effect of Creon 25000 Minimicrospheres on Body Mass Index (BMI) in Patients After Gastrectomy

NCT00160186Phase 4Completed40 enrolled
View all 1 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:
The Role of Sphere Size in the Context of Pancreatin Therapy for Exocrine Pancreatic Insufficiency: A Systematic Review.
Petersen Karl-Uwe, Malfertheiner Peter, Mössner Joachim · J Gastrointestin Liver Dis · 2021
PMID: 33548122Meta-Analysis
Relative bioavailability and pharmacokinetic comparison of a fixed-dose combination tablet of mosapride, pancreatin, and simethicone relative to single-component mosapride tablets in healthy Mexican subjects.
Camarillo Cárdenas Karen Paola, García González Jessica, Argüelles Tello Federico Alberto et al. · Fundam Clin Pharmacol · 2022
PMID: 34837418RCT
The effect of adding pancreatin to standard otilinium bromide and simethicone treatment in type 2 diabetes mellitus patients with irritable bowel syndrome.
Karpuzcu Hulusi Can, Turan Erdoğan Beril, Erdoğan Çağdaş · Sci Rep · 2024
PMID: 39433866ObservationalFull text (PMC)
Differences in In Vitro Properties of Pancreatin Preparations for Pancreatic Exocrine Insufficiency as Marketed in Russia and CIS.
Maev Igor V, Kucheryavyy Yury A, Gubergrits Natalya B et al. · Drugs R D · 2020
PMID: 33211277ObservationalFull text (PMC)
[The effectiveness of pancreatic enzyme replacement therapy using microencapsulated pancreatin preparations in the correction of nutritional status in patients with chronic pancreatitis: a prospective observational study].
Bideeva T V, Maev I V, Kucheryavyy Y A et al. · Ter Arkh · 2020
PMID: 32598660Observational
Characterization of all the lipolytic activities in pancreatin and comparison with porcine and human pancreatic juices.
Salhi Amal, Amara Sawsan, Mansuelle Pascal et al. · Biochimie · 2020
PMID: 31288050Observational
Evaluation of pancreatin stability through enzyme activity determination.
Terra Gleysson De Paula, Vinícius De Farias Marcus, Trevisan Marcello Garcia et al. · Acta Pharm · 2016
PMID: 27383890Observational
Comparative efficiency of microbial enzyme preparations versus pancreatin for in vitro alimentary protein digestion.
Andriamihaja Mireille, Guillot Alain, Svendsen Allan et al. · Amino Acids · 2013
PMID: 22965636Observational
Randomised clinical trial: a 1-week, double-blind, placebo-controlled study of pancreatin 25 000 Ph. Eur. minimicrospheres (Creon 25000 MMS) for pancreatic exocrine insufficiency after pancreatic surgery, with a 1-year open-label extension.
Seiler C M, Izbicki J, Varga-Szabó L et al. · Aliment Pharmacol Ther · 2013
PMID: 23383603ObservationalFull text (PMC)
Randomised clinical trial: the efficacy and safety of pancreatin enteric-coated minimicrospheres (Creon 40000 MMS) in patients with pancreatic exocrine insufficiency due to chronic pancreatitis--a double-blind, placebo-controlled study.
Thorat V, Reddy N, Bhatia S et al. · Aliment Pharmacol Ther · 2012
PMID: 22762290ObservationalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pancreatin (substance)
SNOMED CT
387049005
UMLS CUI
C0030304
RxNorm CUI
7880

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.