Substance / Medication

Recombinant coagulation factor IX

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Model-Based Evaluation of Linear Limited and Bayesian Sparse Sampling for Therapeutic Monitoring of Recombinant Coagulation Factor IX.
Tegenge Million A, Mahmood Iftekhar · J Clin Pharmacol · 2020
PMID: 32501555Observational
Characteristics and Treatment Patterns of Patients with Haemophilia B Receiving Recombinant Coagulation Factor IX.
Park Young-Shil, Hwang Tai Ju, Park Sang Kyu et al. · J Clin Med · 2025
PMID: 40648929OtherFull text (PMC)
Soluble expression of recombinant coagulation factor IX protein using.
Park Byoung-Hee, Yun Hanool, Jeong Hee-Jin · Biochem Biophys Rep · 2024
PMID: 38681671OtherFull text (PMC)
Effect of prepropeptide replacement on γ-carboxylation and activity of recombinant coagulation factor IX.
Vatandoost Jafar, Bos Mettine H A · Biotechnol Lett · 2022
PMID: 35731352Other
Half-life-extended recombinant coagulation factor IX-albumin fusion protein is recycled via the FcRn-mediated pathway.
Chia Jenny, Louber Jade, Glauser Isabelle et al. · J Biol Chem · 2018
PMID: 29523681OtherFull text (PMC)
Investigation of O-glycosylation heterogeneity of recombinant coagulation factor IX using LC-MS/MS.
Seo Youngsuk, Park Gyeong Mi, Oh Myung Jin et al. · Bioanalysis · 2017
PMID: 28920454Other

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Recombinant coagulation factor IX (substance)
SNOMED CT
395860001
UMLS CUI
C2826076

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.