Substance / Medication

Roxithromycin

SNOMED 96037004 UMLS C0035891

Overview

Active Ingredient

roxithromycin

RxNorm CUI

9478

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Legionella pneumonia

Infection by Legionella pneumophilia

Disease caused by Gram-negative bacteria

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Treatment of Rheumatoid Arthritis With Roxithromycin

NCT00439062Phase 4Completed100 enrolled

View all 1 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Evaluation of Roxithromycin as a Treatment Option for Small Abdominal Aortic Aneurysms: An Integrated Study of Meta-analysis and Network Pharmacology.

He Zhen, Chen Yu, Wang Hongjie et al. · Curr Med Chem · 2025

PMID: 38204231Meta-Analysis

Population-based meta-analysis of roxithromycin pharmacokinetics: dosing implications of saturable absorption and protein binding.

Dolton Michael J, D'Argenio David Z · J Antimicrob Chemother · 2017

PMID: 28039274Meta-AnalysisFull text (PMC)

Study of pharmacokinetic interaction of paroxetine and roxithromycin on bencycloquidium bromide in healthy subjects.

Agbokponto Janvier Engelbert, Luo Zhu, Liu Ruijuan et al. · Eur J Pharm Sci · 2015

PMID: 25559065RCT

Effect of low-dose, long-term roxithromycin on airway inflammation and remodeling of stable noncystic fibrosis bronchiectasis.

Liu Jifeng, Zhong Xiaoning, He Zhiyi et al. · Mediators Inflamm · 2014

PMID: 25580060RCTFull text (PMC)

Double-blind, randomized, placebo-controlled study of three-month treatment with the combination of ofloxacin and roxithromycin in recent-onset reactive arthritis.

Kuuliala Antti, Julkunen Heikki, Paimela Leena et al. · Rheumatol Int · 2013

PMID: 23783643RCT

[Impact of treatment with low dose roxithromycin on stable bronchiectasis].

Liu Ji-feng, Zhong Xiao-ning, He Zhi-yi et al. · Zhonghua Jie He He Hu Xi Za Zhi · 2012

PMID: 23290037RCT

Treatment of rheumatoid arthritis with roxithromycin: a randomized trial.

Ogrendik Mesut, Karagoz Nihan · Postgrad Med · 2011

PMID: 21904105RCT

Efficacy of roxithromycin in adult patients with rheumatoid arthritis who had not received disease-modifying antirheumatic drugs: a 3-month, randomized, double-blind, placebo-controlled trial.

Ogrendik Mesut · Clin Ther · 2009

PMID: 19808134RCT

Simultaneous determination and pharmacokinetic study of roxithromycin and ambroxol hydrochloride in human plasma by LC-MS/MS.

Hang Tai-Jun, Zhang Meng, Song Min et al. · Clin Chim Acta · 2007

PMID: 17462615RCT

Long-term antibiotic treatment with roxithromycin in patients with multiple sclerosis.

Woessner R, Grauer M T, Frese A et al. · Infection · 2006

PMID: 17180590RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Roxithromycin (substance)
SNOMED CT: 96037004
UMLS CUI: C0035891
RxNorm CUI: 9478

Clinical Data

This intervention maps to 3 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.