Substance / Medication

Sertraline

Overview

Active Ingredient
sertraline
RxNorm CUI
36437

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

63 trials linked to this intervention

63
Total Trials
5
Recruiting
22
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Comparing the effect of fluoxetine, escitalopram, and sertraline, on the level of BDNF and depression in preclinical and clinical studies: a systematic review.
Talaee Nastaran, Azadvar Shataw, Khodadadi Sanaz et al. · Eur J Clin Pharmacol · 2024
PMID: 38558317Meta-Analysis
Selection of the optimal dose of sertraline for depression: A dose-response meta-analysis of randomized controlled trials.
Luo Xufei, Zhu Di, Li Jitao et al. · Psychiatry Res · 2023
PMID: 37557058Meta-Analysis
Efficacy of omega-3 supplementation on sertraline continuous therapy to reduce depression or anxiety symptoms: A systematic review and meta-analysis.
Chambergo-Michilot Diego, Brañez-Condorena Ana, Falvy-Bockos Ian et al. · Psychiatry Res · 2021
PMID: 33348198Meta-Analysis
Population Pharmacokinetics of Sertraline in Healthy Subjects: a Model-Based Meta-analysis.
Alhadab Ali A, Brundage Richard C · AAPS J · 2020
PMID: 32430638Meta-Analysis
The influence of sertraline on depressive disorder after traumatic brain injury: A meta-analysis of randomized controlled studies.
Gao Caibin, Fu Qiang, Chen PeiPei et al. · Am J Emerg Med · 2019
PMID: 31326198Meta-Analysis
Efficacy of sertraline in post-traumatic brain injury (post-TBI) depression and quality of life: A systematic review and meta-analysis of randomized controlled trials.
Reyes Nikolai Gil D, Espiritu Adrian I, Anlacan Veeda Michelle M · Clin Neurol Neurosurg · 2019
PMID: 31030031Meta-Analysis
Efficacy and safety of sertraline for the treatment of premature ejaculation: Systematic review and meta-analysis.
Yi Zhan-Miao, Chen Shi-Di, Tang Qi-Yu et al. · Medicine (Baltimore) · 2019
PMID: 31169738Meta-AnalysisFull text (PMC)
Effect of sertraline in the treatment and prevention of poststroke depression: A meta-analysis.
Feng Rongfang, Wang Peng, Gao Chenhao et al. · Medicine (Baltimore) · 2018
PMID: 30544429Meta-AnalysisFull text (PMC)
Sertraline use in the first trimester and risk of congenital anomalies: a systemic review and meta-analysis of cohort studies.
Shen Zi-Qi, Gao Shan-Yan, Li Shawn Xiang et al. · Br J Clin Pharmacol · 2017
PMID: 27770542Meta-AnalysisFull text (PMC)
Sertraline and breastfeeding: review and meta-analysis.
Pinheiro Emily, Bogen Debra L, Hoxha Denada et al. · Arch Womens Ment Health · 2015
PMID: 25589155Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sertraline (substance)
SNOMED CT
372594008
UMLS CUI
C0074393
RxNorm CUI
36437

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

4
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
63
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Sertraline — Conditions, Biomarkers & Specialists | Healos | Ltrl