Substance / Medication

Sibutramine

Overview

Active Ingredient
sibutramine
RxNorm CUI
36514

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

6 trials linked to this intervention

6
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Effect of Sibutramine on Plasma C-Reactive Protein, Leptin and Adipon ectin Concentrations: A Systematic Review and Meta-Analysis of Randomized Contr olled Trials.
De Vincentis Antonio, Pedone Claudio, Vespasiani-Gentilucci Umberto et al. · Curr Pharm Des · 2017
PMID: 27719651Meta-Analysis
Long-term changes in blood pressure following orlistat and sibutramine treatment: a meta-analysis.
Johansson K, Sundström J, Neovius K et al. · Obes Rev · 2010
PMID: 20025693Meta-Analysis
Discontinuation due to adverse events in randomized trials of orlistat, sibutramine and rimonabant: a meta-analysis.
Johansson K, Neovius K, DeSantis S M et al. · Obes Rev · 2009
PMID: 19460116Meta-Analysis
Can sibutramine alter systemic blood pressure in obese patients? Systematic review and meta-analysis.
de Lemos Hernani Pinto, Atallah Alvaro Nagib, de Lemos André Luis Alves · Sao Paulo Med J · 2008
PMID: 19274323Meta-AnalysisFull text (PMC)
Orlistat and sibutramine beyond weight loss.
Mannucci Edoardo, Dicembrini Ilaria, Rotella Francesco et al. · Nutr Metab Cardiovasc Dis · 2008
PMID: 17928208Meta-Analysis
Prediction of response to sibutramine therapy in obese non-diabetic and diabetic patients.
Finer N, Ryan D H, Renz C L et al. · Diabetes Obes Metab · 2006
PMID: 16448525Meta-Analysis
The efficacy and safety of sibutramine for weight loss: a systematic review.
Arterburn David E, Crane Paul K, Veenstra David L · Arch Intern Med · 2004
PMID: 15136309Meta-Analysis
Effect of sibutramine on weight loss and blood pressure: a meta-analysis of controlled trials.
Kim Su Hyun, Lee Young Mee, Jee Sun Ha et al. · Obes Res · 2003
PMID: 12972682Meta-Analysis
Metabolic and Inflammatory Changes with Orlistat and Sibutramine Treatment in Obese Malaysian Subjects.
Al-Tahami Belqes Abdullah Mohammad, Al-Safi Ismail Ab Aziz, Sanip Zulkefli et al. · J Nippon Med Sch · 2017
PMID: 28724846RCT
The effects of anti-obesity intervention with orlistat and sibutramine on microvascular endothelial function.
Al-Tahami Belqes Abdullah Mohammad, Ismail Ab Aziz Al-Safi, Bee Yvonne Tee Get et al. · Clin Hemorheol Microcirc · 2015
PMID: 24002121RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sibutramine (substance)
SNOMED CT
386838007
UMLS CUI
C0074493
RxNorm CUI
36514

Clinical Data

This intervention maps to 9 entities in the Ltrl knowledge graph.

1
Conditions
3
Biomarkers
3
Specialists
0
Symptoms
6
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.