Substance / Medication

Sodium oxybate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Long-term Efficacy and Safety of Sodium Oxybate in Treating Alcohol Use Disorder: A Systematic Review and Meta-Analysis.
Biso Letizia, Spini Andrea, Petragnano Francesco et al. · Curr Neuropharmacol · 2025
PMID: 39225220Meta-AnalysisFull text (PMC)
Efficacy and safety of sodium oxybate treatment in adults with narcolepsy and cataplexy: a systematic review and meta-analysis.
Amin Ahmed Mostafa, Hassan Ahmed, Khlidj Yehya et al. · Sleep Breath · 2024
PMID: 39601985Meta-Analysis
Post-marketing and clinical safety experience with sodium oxybate for the treatment of alcohol withdrawal syndrome and maintenance of abstinence in alcohol-dependent subjects.
Addolorato Giovanni, Lesch Otto-Michael, Maremmani Icro et al. · Expert Opin Drug Saf · 2020
PMID: 31876433Meta-Analysis
Sodium oxybate for narcolepsy with cataplexy: systematic review and meta-analysis.
Alshaikh Mashael K, Tricco Andrea C, Tashkandi Mariam et al. · J Clin Sleep Med · 2012
PMID: 22893778Meta-AnalysisFull text (PMC)
Efficacy and Safety of Sodium Oxybate in Adults With Idiopathic Hypersomnia: A Randomized Controlled Trial.
Dauvilliers Yves, Chenini Sofiene, Thobois Ophélie et al. · Neurology · 2025
PMID: 40359459RCT
Effect of sodium oxybate on body mass index in pediatric patients with narcolepsy.
Dauvilliers Yves, Lammers Gert Jan, Lecendreux Michel et al. · J Clin Sleep Med · 2024
PMID: 37942930RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sodium oxybate (substance)
SNOMED CT
410917003
UMLS CUI
C0037537

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.