Substance / Medication

Talc

Overview

Active Ingredient
talc
RxNorm CUI
10323

Indications

1.INDICATIONS AND USAGE 1.1 Malignant Pleural Effusion STERITALC is indicated to decrease the recurrence of malignant pleural effusions in symptomatic patients following maximal drainage of the pleural effusion. 1.2 Pneumothorax STERITALC is indicated in adults to decrease the recurrence of pneumothorax.

Labeler: Novatech SAUpdated: 2025-06-25T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

[see Warnings and Precautions (5.3) and Use in Specific Populations (8.1)]. Due to lead content, STERITALC® is contraindicated in pregnant women and can cause fetal harm and potential loss of pregnancy

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
2
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
A systematic review of the epidemiology evidence on talc and cancer.
Boon Denali, Goodman Julie E, Colonna Kyle J et al. · Crit Rev Toxicol · 2024
PMID: 38868996Meta-Analysis
Talc slurry versus thoracoscopic talc insufflation for malignant pleural effusion: a systematic review and meta-analysis.
Rodrigues Anna Luíza Soares de Oliveira, Souza Maria Eduarda Cavalcanti, Moraes Francisco Cezar Aquino de et al. · J Bras Pneumol · 2024
PMID: 39166590Meta-AnalysisFull text (PMC)
Talc and human cancer: a systematic review of the experimental animal and mechanistic evidence.
Prueitt Robyn L, Drury Nicholas L, Shore Ross A et al. · Crit Rev Toxicol · 2024
PMID: 38979679Meta-Analysis
Occupational exposure to cosmetic talc and mesothelioma in barbers, hairdressers, and cosmetologists: A systematic review of the epidemiology.
Lewis Ryan C, Smith Sierra J, Krevanko Callan F et al. · Toxicol Ind Health · 2023
PMID: 37527434Meta-Analysis
Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc.
Lynch Heather N, Lauer Daniel J, Thompson William J et al. · Front Public Health · 2022
PMID: 36304243Meta-AnalysisFull text (PMC)
Association Between the Frequent Use of Perineal Talcum Powder Products and Ovarian Cancer: a Systematic Review and Meta-analysis.
Woolen Sean A, Lazar Ann A, Smith-Bindman Rebecca · J Gen Intern Med · 2022
PMID: 35112281Meta-AnalysisFull text (PMC)
Complications of thoracoscopic talc insufflation for the treatment of malignant pleural effusions: a meta-analysis.
Zhang Wen, Zhao Yun-Long, Li Shao-Jun et al. · J Cardiothorac Surg · 2021
PMID: 33947423Meta-AnalysisFull text (PMC)
Talc pleurodesis in malignant pleural effusion: a systematic review and meta-analysis.
Beltsios Eleftherios T, Mavrovounis Georgios, Adamou Antonis et al. · Gen Thorac Cardiovasc Surg · 2021
PMID: 33222091Meta-Analysis
Talc exposure and risk of stomach cancer: Systematic review and meta-analysis of occupational cohort studies.
Chang Che-Jui, Tu Yu-Kang, Chen Pau-Chung et al. · J Formos Med Assoc · 2020
PMID: 30100164Meta-Analysis
Talc Pleurodesis: A Medical, Medicolegal, and Socioeconomic Review.
Baiu Ioana, Yevudza Elorm, Shrager Joseph B · Ann Thorac Surg · 2020
PMID: 31593652Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Talc (substance)
SNOMED CT
1557002
UMLS CUI
C0039267
RxNorm CUI
10323
Labeler
Novatech SA

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.