Substance / Medication

Tetracycline hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

120 trials linked to this intervention

120

Total Trials

Recruiting

With Results

Recent Trials

Comparison of Tazarotene and Minocycline Therapies for Maintenance of Facial Acne Vulgaris

NCT00145106Phase 4Completed189 enrolled

Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne Vulgaris

NCT00160394Phase 4Completed130 enrolled

Dalacin-T Gel Post Approval Study

NCT00219570Phase 4Completed134 enrolled

Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency

NCT00243542Phase 4Completed64 enrolled

A Pilot, Multi-Center, Patient Preference Study Comparing Two Clindamycin/Benzoyl Peroxide Gels.

NCT00377000Phase 4Completed60 enrolled

View all 120 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Randomized clinical trial of tetracycline hydrochloride bandage and paste treatments for resolution of lesions and pain associated with digital dermatitis in dairy cattle.

Cutler J H Higginson, Cramer G, Walter J J et al. · J Dairy Sci · 2013

PMID: 24140336RCT

Topical 1% oxytetracycline hydrochloride versus placebo in oral mucosa biopsy.

López-Jornet Pia, Camacho-Alonso Fabio, Martinez-Canovas Ascensión et al. · Dermatol Surg · 2012

PMID: 22455385RCT

Clinical, histologic, and bacteriologic findings in dairy cows with digital dermatitis (footwarts) one month after topical treatment with lincomycin hydrochloride or oxytetracycline hydrochloride.

Berry Steven L, Read Deryck H, Walker Richard L et al. · J Am Vet Med Assoc · 2010

PMID: 20807134RCT

Simultaneous analysis of oxytetracycline hydrochloride, lidocaine, and bromhexine hydrochloride in the presence of many interfering excipients.

Gamal Mohammed, Naguib Ibrahim A, Abdelfatah Rehab M · Arch Pharm (Weinheim) · 2021

PMID: 34131945Observational

Tissue concentrations of sulfamethazine and tetracycline hydrochloride of swine (Sus scrofa domestica) as it relates to withdrawal methods for international export.

Mason Sharon E, Wu Huali, Yeatts Jim E et al. · Regul Toxicol Pharmacol · 2015

PMID: 25707857Observational

The effect of two different demineralization methods with saturated tetracycline hydrochloride on the attachment and growth of gingival fibroblasts. A scanning electron microscopic study.

Babay N, Mokeem S · Odontostomatol Trop · 2005

PMID: 16032945Observational

Investigation of Japanese quail (Coturnix japonica) as a pharmacokinetic model for cockatiels (Nymphicus hollandicus) and Poicephalus parrots via comparison of the pharmacokinetics of a single intravenous injection of oxytetracycline hydrochloride.

Osofsky A, Tell L A, Kass P H et al. · J Vet Pharmacol Ther · 2005

PMID: 16343282Observational

"Tetracycline hydrochloride chemical burn" as self-inflicted mucogingival injury: A rare case report.

Dayakar Mundoor Manjunath, Pai Prakash G, Madhavan Sanupa S · J Indian Soc Periodontol · 2012

PMID: 23055601Case ReportFull text (PMC)

Case of anaphylaxis due to tetracycline hydrochloride.

Ogita Azusa, Takada Kaori, Kawana Seiji · J Dermatol · 2011

PMID: 21352288Case Report

Fibrin glue application in conjunction with tetracycline hydrochloride root conditioning and semilunar coronally repositioned flap in the treatment of gingival recession.

George Joann Pauline, Prabhuji M L V, Shaeesta K B et al. · J Indian Soc Periodontol · 2011

PMID: 21772728Case ReportFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Tetracycline hydrochloride (substance)
SNOMED CT: 16355005
UMLS CUI: C0546879

Clinical Data

This intervention maps to 20 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

120

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.