Substance / Medication

Trazodone hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

48 trials linked to this intervention

48
Total Trials
5
Recruiting
17
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Pharmacokinetics and Bioequivalence Evaluation of Trazodone Hydrochloride Sustained-Release Tablets in Healthy Chinese Volunteers.
Wang Jingyan, Xu Yuan, Zhao Zhicheng et al. · Clin Pharmacol Drug Dev · 2025
PMID: 39587861RCT
[Yimusake alone or combined with trazodone hydrochloride for primary premature ejaculation].
Xu Ji-Xiu, Gao Guo, Xu Ning et al. · Zhonghua Nan Ke Xue · 2012
PMID: 22574377RCT
Development of Palatable Amorphous Trazodone Hydrochloride Formulations via Ion Exchange.
Li Zhaohua, Wang Junjie, Wang Huijian et al. · Pharmaceutics · 2025
PMID: 40870995OtherFull text (PMC)
Influence of Genetic Polymorphisms on the Pharmacokinetics of Trazodone Hydrochloride: A Scoping Review and Future Perspective.
Meulman Jessica, Visacri Marília Berlofa, Moriel Patricia et al. · Ther Drug Monit · 2023
PMID: 36191287Other
Sustained-release Drug Delivery System of Trazodone Hydrochloride Based on Electrospray Technology: Preparation, Characterization, In vitro and In vivo Evaluation.
Wang Chengwei, Wang Haiqiao, Adu-Frimpong Michael et al. · AAPS PharmSciTech · 2025
PMID: 41366168Preclinical
The effect of preanaesthetic oral trazodone hydrochloride on the induction dose of propofol: a preliminary retrospective study.
Walters Kate, Gittel Claudia, Brearley Jacqueline C · Vet Anaesth Analg · 2022
PMID: 35715325Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Trazodone hydrochloride (substance)
SNOMED CT
58956008
UMLS CUI
C0282369

Clinical Data

This intervention maps to 8 entities in the Healos knowledge graph.

2
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
48
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.