Substance / Medication

Ursodeoxycholic acid

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
The effects of ursodeoxycholic acid on cardiometabolic risk factors: a systematic review and meta-analysis of randomized controlled trials.
Rashidbeygi Elaheh, Rasaei Niloufar, Amini Mohammad Reza et al. · BMC Cardiovasc Disord · 2025
PMID: 39984850Meta-AnalysisFull text (PMC)
MGAT5/TMEM163 variant is associated with prognosis in ursodeoxycholic acid-treated patients with primary biliary cholangitis.
Wang Hanxiao, Li You, Pu Xiting et al. · J Gastroenterol · 2024
PMID: 37845416Meta-Analysis
Neuroprotective Effect of Tauroursodeoxycholic Acid (TUDCA) onandModels of Retinal Disorders: A Systematic Review.
Li Jiaxian, Huang Ziyang, Jin Yu et al. · Curr Neuropharmacol · 2024
PMID: 37691227Meta-AnalysisFull text (PMC)
Ursodeoxycholic acid for preventing parenteral nutrition-associated cholestasis in neonates: A systematic review and meta-analysis.
Anne Rajendra Prasad, Kadyada Srikanth Puttaiah, Aradhya Abhishek Somasekhara et al. · Fundam Clin Pharmacol · 2024
PMID: 38342497Meta-Analysis
Role of Ursodeoxycholic Acid in the Prevention of Gallstones Formation in Bariatric Patients-a Systematic Review and Meta-Analysis of Randomised Trials.
Sharma Amit, Shanti Hiba, Nageswaran Haritharan et al. · Obes Surg · 2023
PMID: 37872257Meta-Analysis
Treatment response to ursodeoxycholic acid in primary biliary cholangitis: A systematic review and meta-analysis.
Gazda Jakub, Drazilova Sylvia, Gazda Matej et al. · Dig Liver Dis · 2023
PMID: 36593158Meta-Analysis
Efficacy and Safety of Bezafibrate Alone or in Combination with Ursodeoxycholic Acid in Primary Biliary Cholangitis: Systematic Review and Meta-Analysis.
Khakoo Nidah Shabbir, Sultan Shahnaz, Reynolds John M et al. · Dig Dis Sci · 2023
PMID: 36180756Meta-Analysis
Ursodeoxycholic acid in the management of symptomatic gallstone disease: systematic review and clinician survey.
Hall Lewis, Halle-Smith James, Evans Richard et al. · BJS Open · 2023
PMID: 36952251Meta-AnalysisFull text (PMC)
Efficacy and safety of ursodeoxycholic acid in children with cholestasis: A systematic review and meta-analysis.
Huang Liang, Li Siyu, Chen Jingjing et al. · PLoS One · 2023
PMID: 36719881Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Ursodeoxycholic acid (substance)
SNOMED CT
41143004
UMLS CUI
C0042105

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.