No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

A Trial of Thiamin Supplementation in Patients With Heart Failure

NCT00959075Phase 4Completed70 enrolled

The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine

NCT03746106Phase 4Completed7 enrolled

View all 2 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Effect of vitamin B1 supplementation on blood creatinine and lactate levels and clinical outcomes in patients in intensive care units: a systematic review and meta-analysis of randomized controlled trials.

Karimi Elmira, Gholizadeh Mohammad, Abdolahi Mina et al. · Nutr Rev · 2024

PMID: 37553224Meta-Analysis

Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis.

Wu Yanjun, Zhang Liming, Li Suyun et al. · Nutr Rev · 2022

PMID: 33912967Meta-Analysis

Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis.

Fujii Tomoko, Salanti Georgia, Belletti Alessandro et al. · Intensive Care Med · 2022

PMID: 34750650Meta-AnalysisFull text (PMC)

[Therapeutic effect of hydrocortisone combined with vitamin C and vitamin B1 on patients with sepsis: a Meta-analysis].

Chang Chenyang, Luo Kaiyuan, Zhu Huifang et al. · Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · 2021

PMID: 34839858Meta-Analysis

Vitamin B1 Intake and the Risk of Colorectal Cancer: a Systematic Review of Observational Studies.

Liu Yan, Xiong Wen-Jing, Wang Lei et al. · J Nutr Sci Vitaminol (Tokyo) · 2021

PMID: 34980717Meta-Analysis

Impact of Vitamin B1 and Vitamin B2 Supplementation on Anxiety, Stress, and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.

Tao Yingxuan, Wu Murong, Su Boyao et al. · Nutrients · 2025

PMID: 40507089RCTFull text (PMC)

Effects of hydrocortisone combined with vitamin C and vitamin B1 versus hydrocortisone alone on microcirculation in septic shock patients: A pilot study.

Wang Jinlong, Song Qianwen, Yang Shuhe et al. · Clin Hemorheol Microcirc · 2023

PMID: 36911931RCTFull text (PMC)

The Utility of Oral Vitamin B1 and Mecobalamin to Improve Corneal Nerves in Dry Eye Disease: An In Vivo Confocal Microscopy Study.

Ren Xiaotong, Chou Yilin, Wang Yuexin et al. · Nutrients · 2022

PMID: 36145126RCTFull text (PMC)

The effect of vitamin B1 on bleeding and spotting in women using an intrauterine device: a double-blind randomised controlled trial.

Jafari Azam, Abedi Parvin, Sayahi Masumeh et al. · Eur J Contracept Reprod Health Care · 2014

PMID: 24738933RCT

[Thiamine (vitamin B1) treatment in patients with alcohol dependence].

Dervaux Alain, Laqueille Xavier · Presse Med · 2017

PMID: 27818067Review

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Thiamine (substance)
SNOMED CT: 259659006
UMLS CUI: C0039840
RxNorm CUI: 10454
Labeler: REMEDYREPACK INC.

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.