Substance / Medication

Vitamin D>3<

Overview

Active Ingredient
cholecalciferol
RxNorm CUI
2418

Indications

Folarex is a prescription multivitamin/multi-mineral dietary supplement formulated for the clinical dietary management of a suboptimal nutritional status in patients where advanced folate, vitamin B supplementation, and maintenance of good health is needed.

Labeler: Oncora Pharma, LLCUpdated: 2026-02-25T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Folarex is contraindicated in patients with a known hypersensitivity to any of the ingredients.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

152 trials linked to this intervention

152
Total Trials
27
Recruiting
64
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Dietary fat increases vitamin D-3 absorption.
Dawson-Hughes Bess, Harris Susan S, Lichtenstein Alice H et al. · J Acad Nutr Diet · 2015
PMID: 25441954RCT
Pharmacokinetics of oral vitamin D(3) and calcifediol.
Jetter Alexander, Egli Andreas, Dawson-Hughes Bess et al. · Bone · 2014
PMID: 24516879RCT
The effects of vitamin D(3) supplementation on serum total 25[OH]D concentration and physical performance: a randomised dose-response study.
Close Graeme L, Leckey Jill, Patterson Marcelle et al. · Br J Sports Med · 2013
PMID: 23410885RCT
Bioavailability of alendronate and vitamin D(3) in an alendronate/vitamin D(3) combination tablet.
Denker Andrew E, Lazarus Nicole, Porras Arturo et al. · J Clin Pharmacol · 2011
PMID: 21148044RCT
The ratio of serum 24,25-dihydroxyvitamin D(3) to 25-hydroxyvitamin D(3) is predictive of 25-hydroxyvitamin D(3) response to vitamin D(3) supplementation.
Wagner Dennis, Hanwell Heather E, Schnabl Kareena et al. · J Steroid Biochem Mol Biol · 2011
PMID: 21605672RCT
Effect of vitamin D(3) and calcium on fracture risk in 65- to 71-year-old women: a population-based 3-year randomized, controlled trial--the OSTPRE-FPS.
Salovaara Kari, Tuppurainen Marjo, Kärkkäinen Matti et al. · J Bone Miner Res · 2010
PMID: 20200964RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Colecalciferol (substance)
SNOMED CT
18414002
UMLS CUI
C0008318
RxNorm CUI
2418
Labeler
Oncora Pharma, LLC

Clinical Data

This intervention maps to 16 entities in the Ltrl knowledge graph.

10
Conditions
2
Biomarkers
2
Specialists
0
Symptoms
152
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.