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PATRICIA J SIME MD
MD
Pulmonary Disease Physician
NPI: 1003841768IndividualAccepts Medicare
Specialties, Licenses & Credentials
Pulmonary Disease PhysicianPrimary
Internal Medicine — Pulmonary Disease
Code: 207RP1001X
0101266609(VA)
Education
OTHER
Class of 1988
Research & Publications (20)
Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
PMID 19286977·Am J Respir Cell Mol Biol·2009
8-other
RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke.
PMID 18688039·Am J Respir Cell Mol Biol·2009
7-preclinical
Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies.
PMID 18528522·PPAR Res·2008
8-other
High-dose but not low-dose mainstream cigarette smoke suppresses allergic airway inflammation by inhibiting T cell function.
PMID 18567739·Am J Physiol Lung Cell Mol Physiol·2008
7-preclinical
Targeting cyclooxygenase-2 in hematological malignancies: rationale and promise.
PMID 18691115·Curr Pharm Des·2008
6-review
The aryl hydrocarbon receptor attenuates tobacco smoke-induced cyclooxygenase-2 and prostaglandin production in lung fibroblasts through regulation of the NF-kappaB family member RelB.
PMID 18697742·J Biol Chem·2008
7-preclinical
Cigarette smoke-induced expression of heme oxygenase-1 in human lung fibroblasts is regulated by intracellular glutathione.
PMID 18689604·Am J Physiol Lung Cell Mol Physiol·2008
8-other
The antifibrogenic potential of PPARgamma ligands in pulmonary fibrosis.
PMID 18317437·J Investig Med·2008
6-review
Exogenous lipoid pneumonia: an unexpected complication of substance abuse.
PMID 18765715·Ann Intern Med·2008
5-case
Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB.
PMID 17322371·Am J Pathol·2007
7-preclinical
TGF-beta, Smad3 and the process of progressive fibrosis.
PMID 17635115·Biochem Soc Trans·2007
6-review
Severe airflow obstruction and eosinophilic lung disease after Stevens-Johnson syndrome.
PMID 17138682·Eur Respir J·2006
5-case
Antenatal Ureaplasma urealyticum respiratory tract infection stimulates proinflammatory, profibrotic responses in the preterm baboon lung.
PMID 16864693·Pediatr Res·2006
7-preclinical
More than structural cells, fibroblasts create and orchestrate the tumor microenvironment.
PMID 16916756·Immunol Invest·2006
6-review
Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema.
PMID 16443644·Am J Physiol Lung Cell Mol Physiol·2006
8-other
Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation.
PMID 16908446·Exp Lung Res·2006
4-observational
The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts.
PMID 15863442·Am J Physiol Lung Cell Mol Physiol·2005
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 9000 STONY POINT PKWY
RICHMOND, VA 23235 - Phone
- (804) 560-8921
Quick Facts
- NPI
- 1003841768
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 1
- Locations
- 1
- Years in Practice
- 38
- Publications
- 20
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