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ROLAND PIXLEY, MD
MD
Obstetrics & Gynecology Physician
NPI: 1023034311Individual
Specialties, Licenses & Credentials
Research & Publications (20)
Cleaved high-molecular-weight kininogen and its domain 5 inhibit migration and invasion of human prostate cancer cells through the epidermal growth factor receptor pathway.
PMID 19483730·Oncogene·2009
8-other
A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A.
PMID 18394675·Bioorg Chem·2008
8-other
The inhibition of tube formation in a collagen-fibrinogen, three-dimensional gel by cleaved kininogen (HKa) and HK domain 5 (D5) is dependent on Src family kinases.
PMID 18062965·Exp Cell Res·2008
8-other
Fifty years of research on the plasma kallikrein-kinin system: from protein structure and function to cell biology and in-vivo pathophysiology.
PMID 17597995·Thromb Haemost·2007
6-review
Domain 5 of kininogen inhibits proliferation of human colon cancer cell line (HCT-116) by interfering with G1/S in the cell cycle.
PMID 17155949·J Thromb Haemost·2007
8-other
New insights from the structure-function analysis of the catalytic region of human platelet phosphodiesterase 3A: a role for the unique 44-amino acid insert.
PMID 16873361·J Biol Chem·2006
8-other
Multiple myeloma in a murine syngeneic model:modulation of growth and angiogenesis by a monoclonal antibody to kininogen.
PMID 16187087·Cancer Immunol Immunother·2006
7-preclinical
Modulation of inflammation by kininogen deficiency in a rat model of inflammatory arthritis.
PMID 16059911·Arthritis Rheum·2005
7-preclinical
A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat.
PMID 15987478·Arthritis Res Ther·2005
4-observational
A monoclonal antibody to high-molecular weight kininogen is therapeutic in a rodent model of reactive arthritis.
PMID 15331420·Am J Pathol·2004
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 1025 MOREHEAD MEDICAL DR, STE 400
CHARLOTTE, NC 28204 - Phone
- (704) 446-1700
Locations (5)
Practice Location
1025 MOREHEAD MEDICAL DR, CHARLOTTE, NC
(704) 446-1700
Practice Location
9908 COULOAK DR, CHARLOTTE, NC
(704) 801-2075
Practice Location
4525 CAMERON VALLEY PKWY, CHARLOTTE, NC
(704) 446-1700
Practice Location
7810 PROVIDENCE RD, CHARLOTTE, NC
(704) 446-1700
Practice Location
16455 STATESVILLE RD, HUNTERSVILLE, NC
(704) 896-3370
Quick Facts
- NPI
- 1023034311
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 5
- Publications
- 20
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