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MICHAEL AXELSON, M.D.
M.D.
Medical Oncology Physician
NPI: 1073615654Individual
Specialties, Licenses & Credentials
Research & Publications (20)
Aberrant intracellular IGF-1R beta-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation.
PMID 19302825·Exp Cell Res·2009
7-preclinical
Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
PMID 19032680·Acta Ophthalmol·2008
4-observational
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
PMID 19032679·Acta Ophthalmol·2008
7-preclinical
Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
PMID 18515591·Invest Ophthalmol Vis Sci·2008
7-preclinical
Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
PMID 18515579·Invest Ophthalmol Vis Sci·2008
4-observational
CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling.
PMID 18331353·FEBS J·2008
7-preclinical
Differential roles of SS18-SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth.
PMID 18267106·Biochem Biophys Res Commun·2008
4-observational
Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
PMID 18070930·Mol Pharmacol·2008
8-other
Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
PMID 19032681·Acta Ophthalmol·2008
7-preclinical
Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and beta-arrestin1.
PMID 17828296·Oncogene·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 2711 RANDOLPH RD, SUITE 100
CHARLOTTE, NC 28207 - Phone
- (704) 342-1900
Quick Facts
- NPI
- 1073615654
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 2
- Locations
- 1
- Publications
- 20
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