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MRS. SIMONA FLORINA CONSTANTINESCU MD
MD
Family Medicine Physician
NPI: 1144429465IndividualAccepts Medicare
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
MD440448(PA)50105(CT)
Geriatric Medicine (Family Medicine) Physician
Family Medicine — Geriatric Medicine
Code: 207QG0300X
MD440448(PA)
Hospitalist Physician
Hospitalist
Code: 208M00000X
50105(CT)
Student in an Organized Health Care Education/Training Program
Student in an Organized Health Care Education/Training Program
Code: 390200000X
E-6408(AR)
Education
OTHER
Class of 1994
Research & Publications (20)
A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis.
PMID 19164538·Proc Natl Acad Sci U S A·2009
7-preclinical
Structural changes of piezoelectric La3Ga5SiO14 induced by paramagnetic ions revealed by 71Ga multiple quantum magic angle spinning.
PMID 19596562·Solid State Nucl Magn Reson·2009
8-other
Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.
PMID 19139102·J Biol Chem·2009
7-preclinical
A new era for small molecule screening: from new targets, such as JAK2 V617F, to complex cellular screens.
PMID 19183237·J Cell Mol Med·2009
8-other
Ligand-independent thrombopoietin mutant receptor requires cell surface localization for endogenous activity.
PMID 19261614·J Biol Chem·2009
7-preclinical
SOCS3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative neoplasms associated with mutant JAK2 kinases.
PMID 19229050·Haematologica·2009
7-preclinical
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
PMID 19620628·J Exp Med·2009
7-preclinical
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia.
PMID 18362173·J Exp Med·2008
7-preclinical
JAK kinases overexpression promotes in vitro cell transformation.
PMID 17873904·Oncogene·2008
7-preclinical
The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor.
PMID 18456658·J Biol Chem·2008
8-other
Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif.
PMID 18474601·J Biol Chem·2008
8-other
The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes.
PMID 18216297·Blood·2008
7-preclinical
The JAK2V617F mutation can occur in a hematopoietic stem cell that exhibits no proliferative advantage: a case of human allogeneic transplantation.
PMID 18650474·Blood·2008
5-case
Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs.
PMID 18201969·J Biol Chem·2008
7-preclinical
Introduction to 'A special spotlight review series on BCR-ABL-negative myeloproliferative neoplasms'.
PMID 18197171·Leukemia·2008
8-other
Substitution of pseudokinase domain residue Val-617 by large non-polar amino acids causes activation of JAK2.
PMID 18326042·J Biol Chem·2008
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via PINNACLE HEALTH MEDICAL SERVICES · 2 locations total
- Address
- 4400 CARLISLE PIKE
CAMP HILL, PA 17011 - Phone
- (717) 975-9800
Quick Facts
- NPI
- 1144429465
- Entity Type
- Individual
- Gender
- Female
- Medicare
- Accepted
- Specialties
- 5
- Locations
- 2
- Years in Practice
- 32
- Publications
- 20
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