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DAVID CALDERWOOD, MD
MD
Family Medicine Physician
NPI: 1235110586Individual
Specialties, Licenses & Credentials
Family Medicine PhysicianPrimary
Family Medicine
Code: 207Q00000X
10438(AL)
Research & Publications (20)
Competition for talin results in trans-dominant inhibition of integrin activation.
PMID 15143061·J Biol Chem·2004
7-preclinical
Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
PMID 12039590·Bioorg Med Chem Lett·2002
8-other
The phosphotyrosine binding-like domain of talin activates integrins.
PMID 11932255·J Biol Chem·2002
7-preclinical
Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration.
PMID 11781567·Nat Cell Biol·2001
7-preclinical
Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling.
PMID 10801899·J Biol Chem·2000
6-review
Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension.
PMID 19458194·Mol Biol Cell·2009
7-preclinical
The role of FilGAP-filamin A interactions in mechanoprotection.
PMID 19144823·Mol Biol Cell·2009
7-preclinical
Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects.
PMID 19240021·J Biol Chem·2009
7-preclinical
The E3 ubiquitin ligase specificity subunit ASB2beta is a novel regulator of muscle differentiation that targets filamin B to proteasomal degradation.
PMID 19300455·Cell Death Differ·2009
7-preclinical
Structural basis of the migfilin-filamin interaction and competition with integrin beta tails.
PMID 18829455·J Biol Chem·2008
7-preclinical
JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.
PMID 19064666·J Cell Biol·2008
8-other
The structural basis of integrin-linked kinase-PINCH interactions.
PMID 19074270·Proc Natl Acad Sci U S A·2008
8-other
The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins.
PMID 18165225·J Biol Chem·2008
7-preclinical
Structure of three tandem filamin domains reveals auto-inhibition of ligand binding.
PMID 17690686·EMBO J·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 420 LOWELL DR SE, SUITE 201
HUNTSVILLE, AL 35801 - Phone
- (256) 535-5944
Quick Facts
- NPI
- 1235110586
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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