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WILLIAM HUMPHREYS, M.D.
M.D.
Orthopaedic Surgery Physician
NPI: 1235131814Individual
Specialties, Licenses & Credentials
Research & Publications (20)
Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections.
PMID 19251818·Drug Metab Dispos·2009
7-preclinical
Apixaban metabolism and pharmacokinetics after oral administration to humans.
PMID 18832478·Drug Metab Dispos·2009
8-other
Metabolism and excretion of an oral taxane analog, [14C]3'-tert-butyl-3'-N-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-N-debenzoyl-4-O-methoxy-paclitaxel (BMS-275183), in rats and dogs.
PMID 19196843·Drug Metab Dispos·2009
4-observational
Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans.
PMID 19420130·Drug Metab Dispos·2009
3-trial
Bioactivation of coumarin in rat olfactory mucosal microsomes: Detection of protein covalent binding and identification of reactive intermediates through analysis of glutathione adducts.
PMID 19576871·Chem Biol Interact·2009
7-preclinical
In vitro screening of 50 highly prescribed drugs for thiol adduct formation--comparison of potential for drug-induced toxicity and extent of adduct formation.
PMID 19253935·Chem Res Toxicol·2009
8-other
Fine-scale comparative phylogeography of a sympatric sister species triplet of subterranean diving beetles from a single calcrete aquifer in Western Australia.
PMID 19674311·Mol Ecol·2009
7-preclinical
CYP3A4-mediated ester cleavage as the major metabolic pathway of the oral taxane 3'-tert-butyl-3'-N-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-N-debenzoyl-4-O-methoxycarbonyl-paclitaxel (BMS-275183).
PMID 19158314·Drug Metab Dispos·2009
8-other
The pneumotoxin 3-methylindole is a substrate and a mechanism-based inactivator of CYP2A13, a human cytochrome P450 enzyme preferentially expressed in the respiratory tract.
PMID 19608696·Drug Metab Dispos·2009
7-preclinical
Sulfation of o-demethyl apixaban: enzyme identification and species comparison.
PMID 19131519·Drug Metab Dispos·2009
4-observational
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
Via practice · 5 locations total
- Address
- 2016 S MAIN ST
MARYVILLE, MO 64468 - Phone
- (660) 562-2525
Locations (5)
Practice Location
2016 S MAIN ST, MARYVILLE, MO
(660) 562-2525
Practice Location
114 E SOUTH HILLS DR, MARYVILLE, MO
(660) 562-2525
Practice Location
2016 S MAIN ST, MARYVILLE, MO
(660) 562-2600
Practice Location
3107 FREDERICK AVE, SAINT JOSEPH, MO
(816) 233-9888
Practice Location
301 E Price Ave, Savannah, MO
(816) 432-0006
Quick Facts
- NPI
- 1235131814
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 5
- Publications
- 20
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