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LAWRENCE KIRSCHNER, M.D.
M.D.
Endocrinology, Diabetes & Metabolism Physician
NPI: 1265449433Individual
Specialties, Licenses & Credentials
Endocrinology, Diabetes & Metabolism PhysicianPrimary
Internal Medicine — Endocrinology, Diabetes & Metabolism
Code: 207RE0101X
35081774(OH)
Research & Publications (20)
Use of mouse models to understand the molecular basis of tissue-specific tumorigenesis in the Carney complex.
PMID 19522826·J Intern Med·2009
6-review
Emerging treatment strategies for adrenocortical carcinoma: a new hope.
PMID 16234301·J Clin Endocrinol Metab·2006
6-review
A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.
PMID 15930266·Cancer Res·2005
7-preclinical
Clinical and genetic heterogeneity, overlap with other tumor syndromes, and atypical glucocorticoid hormone secretion in adrenocorticotropin-independent macronodular adrenal hyperplasia compared with other adrenocortical tumors.
PMID 19509103·J Clin Endocrinol Metab·2009
4-observational
Mutations in regulatory subunit type 1A of cyclic adenosine 5'-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes.
PMID 19293268·J Clin Endocrinol Metab·2009
8-other
The Carney complex gene PRKAR1A plays an essential role in cardiac development and myxomagenesis.
PMID 19577711·Trends Cardiovasc Med·2009
6-review
Mouse model for bilateral adrenal hyperplasia.
PMID 19286161·Ann Endocrinol (Paris)·2009
7-preclinical
Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1.
PMID 19424295·EMBO Rep·2009
7-preclinical
Pituitary-specific knockout of the Carney complex gene Prkar1a leads to pituitary tumorigenesis.
PMID 17975024·Mol Endocrinol·2008
7-preclinical
Development of a pituitary-specific cre line targeted to the Pit-1 lineage.
PMID 18196598·Genesis·2008
7-preclinical
Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.
PMID 18316483·Circulation·2008
7-preclinical
Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.
PMID 18953430·Neoplasia·2008
7-preclinical
Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A.
PMID 17932105·Mol Endocrinol·2008
7-preclinical
Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.
PMID 18413734·Cancer Res·2008
7-preclinical
Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region.
PMID 17554679·Int J Dev Biol·2007
7-preclinical
2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase.
PMID 17673571·Mol Pharmacol·2007
8-other
A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia.
PMID 16767104·Nat Genet·2006
8-other
Editorial: paradigms for adrenal cancer: think globally, act locally.
PMID 17088440·J Clin Endocrinol Metab·2006
8-other
Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.
PMID 16288019·Cancer Res·2005
7-preclinical
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
Contact & Hours
- Address
- 2050 KENNY RD FL 10
COLUMBUS, OH 43221 - Phone
- (614) 685-3333
Quick Facts
- NPI
- 1265449433
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Not confirmed
- Specialties
- 1
- Locations
- 1
- Publications
- 20
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