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MARK WITTMAN, MD
MD
Critical Care Medicine (Anesthesiology) Physician
NPI: 1295723708IndividualAccepts Medicare
Specialties, Licenses & Credentials
Anesthesiology — Critical Care Medicine
Code: 207LC0200X
G45108(CA)
Education
NORTHWESTERN UNIVERSITY FEINBERG MEDICAL SCHOOL
Class of 1980
Research & Publications (15)
Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase.
PMID 17187980·Bioorg Med Chem Lett·2007
7-preclinical
Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity.
PMID 16134929·J Med Chem·2005
7-preclinical
Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
PMID 11277526·Bioorg Med Chem Lett·2001
7-preclinical
Synthesis of metabolically blocked paclitaxel analogues.
PMID 11277525·Bioorg Med Chem Lett·2001
8-other
Discovery and evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an orally efficacious inhibitor of insulin-like growth factor-1 receptor kinase with broad spectrum in vivo antitumor activity.
PMID 18763755·J Med Chem·2008
7-preclinical
Balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-IR inhibitors.
PMID 18572407·Bioorg Med Chem Lett·2008
8-other
2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethanamine side chain variants of the IGF-1R inhibitor BMS-536924.
PMID 18258427·Bioorg Med Chem Lett·2008
7-preclinical
Thyroxine increases the rate but does not alter the pattern of innervation during embryonic chick corneal development.
PMID 18172086·Invest Ophthalmol Vis Sci·2008
7-preclinical
Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to improve cytochrome P450 profile.
PMID 17398093·Bioorg Med Chem Lett·2007
7-preclinical
Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R).
PMID 17317169·Bioorg Med Chem Lett·2007
8-other
Data courtesy of the U.S. National Library of Medicine (NLM). Ltrl is not affiliated with or endorsed by NLM.
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Contact & Hours
- Address
- 120 S SPALDING DR, STE. #301
BEVERLY HILLS, CA 90212 - Phone
- (310) 385-7755
Quick Facts
- NPI
- 1295723708
- Entity Type
- Individual
- Gender
- Male
- Medicare
- Accepted
- Specialties
- 3
- Locations
- 1
- Years in Practice
- 46
- Publications
- 15
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